EC Number   |
Protein Variants |
Reference |
|---|
   3.4.21.42 | Q340E |
activation by complement component C1r is impaired, enhanced glycosylation at N391 |
669727 |
| 3.4.21.42 | C1s(MASP-2 CCP1/2) |
chimeric C1s protease containing the MASP-2 complement control protein domain, cleavage efficiency of C4 similar to MASP-2 protease |
665686 |
| 3.4.21.42 | C1s(MASP-2 SP) |
chimeric C1s protease containing the MASP-2 serine protease domain, cleavage efficiency similar to wild-type C1s |
665686 |
| 3.4.21.42 | D343N |
complement component C4 cleavage activity below 50% compared to wild-type, complement component C2 cleavage activity similar to wild-type |
669727 |
| 3.4.21.42 | P341I |
complement component C4 cleavage activity below 50% compared to wild-type, complement component C2 cleavage activity similar to wild-type |
669727 |
| 3.4.21.42 | Q340D |
complement component C4 cleavage activity below 50% compared to wild-type, complement component C2 cleavage activity similar to wild-type |
669727 |
| 3.4.21.42 | Q340D/D343E |
complement component C4 cleavage activity below 50% compared to wild-type, complement component C2 cleavage activity similar to wild-type |
669727 |
| 3.4.21.42 | Q340E/D343N |
complement component C4 cleavage activity below 50% compared to wild-type, complement component C2 cleavage activity similar to wild-type |
669727 |
| 3.4.21.42 | Q340K |
complement component C4 cleavage activity below 50% compared to wild-type, complement component C2 cleavage activity similar to wild-type |
669727 |
| 3.4.21.42 | Q340K/D343N |
complement component C4 cleavage activity below 50% compared to wild-type, complement component C2 cleavage activity similar to wild-type |
669727 |
