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EC Number
Protein Variants
Commentary
Reference
3.2.1.165
D469A
inactive mutant enzyme
680031
,
680406
3.2.1.165
D469E
inactive mutant enzyme
680031
,
680406
3.2.1.165
E541D
inactive mutant enzyme
680031
,
680406
3.2.1.165
E541Q
inactive mutant enzyme
680031
,
680406
3.2.1.165
S468N/D469E
inactive mutant enzyme
680031
,
680406
3.2.1.165
D469A
catalytic acid/base
699562
3.2.1.165
E541A
catalytic nucleophile
699562
3.2.1.165
D464A
specific acitivity is 0.44% compared to the activity of the wild-type enzyme
748421
3.2.1.165
D464E
no activity
748421
3.2.1.165
D464E/E539D
no activity
748421
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