EC Number |
Protein Variants |
Reference |
---|
2.7.8.B13 | A90Y |
about 25% of wild-type activity |
-, 760904 |
2.7.8.B13 | more |
an artificial gene construct for a protein homologous to phosphatidylinositol phosphate synthase of Mycobacterium tuberculosis and archaetidylinositol phosphate synthase of Methanothermobacter thermautotrophicus is cloned in Escherichia coli and introduced into Corynebacterium glutamicum cells. The recombinant cells show afterwards both, phosphatidylinositol phosphate synthase and archaetidylinositol phosphate synthase activities, 175 pmol/h/mg and 174 pmol/h/mg, respectively, but no phosphatidylinositol synthase activity is detected, overview |
726887 |
2.7.8.B13 | more |
an artificial gene construct for a protein homologous to phosphatidylinositol phosphate synthase of Mycobacterium tuberculosis and archaetidylinositol phosphate synthase of Methanothermobacter thermautotrophicus is cloned in Escherichia coli and introduced into Mycobacterium bovis cells. The recombinant cells show afterwards both, phosphatidylinositol phosphate synthase and archaetidylinositol phosphate synthase activities, 138 pmol/h/mg and 5 pmol/h/mg, respectively, but no phosphatidylinositol synthase activity is detected, overview |
726887 |
2.7.8.B13 | more |
an artificial gene construct for a protein homologous to phosphatidylinositol phosphate synthase of Mycobacterium tuberculosis and archaetidylinositol phosphate synthase of Methanothermobacter thermautotrophicus is cloned in Escherichia coli and introduced into Propionibacterium acnes cells. The recombinant cells show afterwards both, phosphatidylinositol phosphate synthase and archaetidylinositol phosphate synthase activities, 88 pmol/h/mg and 14 pmol/h/mg, respectively, but no phosphatidylinositol synthase activity is detected, overview |
726887 |
2.7.8.B13 | more |
an artificial gene construct for a protein homologous to phosphatidylinositol phosphate synthase of Mycobacterium tuberculosis and archaetidylinositol phosphate synthase of Methanothermobacter thermautotrophicus is cloned in Escherichia coli and introduced into Rhodococcus equi cells. The recombinant cells show afterwards both, phosphatidylinositol phosphate synthase and archaetidylinositol phosphate synthase activities, 124 pmol/h/mg and 33 pmol/h/mg, respectively, but no phosphatidylinositol synthase activity is detected, overview |
726887 |
2.7.8.B13 | more |
an artificial gene construct for a protein homologous to phosphatidylinositol phosphate synthase of Mycobacterium tuberculosis and archaetidylinositol phosphate synthase of Methanothermobacter thermautotrophicus is cloned in Escherichia coli and introduced into Streptomyces avermitilis cells. The recombinant cells show afterwards both, phosphatidylinositol phosphate synthase and archaetidylinositol phosphate synthase activities, 76 pmol/h/mg and 20 pmol/h/mg, respectively, but no phosphatidylinositol synthase activity is detected, overview |
726887 |
2.7.8.B13 | R137K |
about 115% of wild-type activity |
-, 760904 |
2.7.8.B13 | R137Q |
about 40% of wild-type activity |
-, 760904 |
2.7.8.B13 | R94K |
about 20% of wild-type activity |
760904 |
2.7.8.B13 | R94Q |
about 15% of wild-type activity |
-, 760904 |