EC Number   |
Protein Variants |
Reference |
|---|
    2.7.4.26 | A53V |
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme, the mutant shows increased activity compared to the wild-type enzyme |
739681 |
| 2.7.4.26 | F83A/I86A/I156A |
the mutant shows a 27% rate of conversion of (2E,6E)-farnesyl phosphate to (2E,6E)-farnesyl diphosphate. The reaction is not catalyzed by the wild-type enzyme |
-, 717483 |
| 2.7.4.26 | G44A |
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme |
739681 |
| 2.7.4.26 | G45A |
site-directed mutagenesis, the mutant shows increased activity compared to the wild-type enzyme |
739681 |
| 2.7.4.26 | G49A |
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme |
739681 |
| 2.7.4.26 | H60Q |
His60 plays a key role in binding and catalysis, the mutant enzyme shows increased values for Km and decreased vaules for kcat and kcat/Km |
-, 717483 |
| 2.7.4.26 | I140V |
site-directed mutagenesis, the mutant shows highly increased activity compared to the wild-type enzyme |
739681 |
| 2.7.4.26 | K204A |
kinetic values similar to wild-type |
717264 |
| 2.7.4.26 | K204A |
site-directed mutagenesis, the mutant shows highly increased activity compared to the wild-type enzyme |
739681 |
| 2.7.4.26 | K204G |
site-directed mutagenesis, the mutant shows increased activity compared to the wild-type enzyme |
739681 |
