EC Number   |
Protein Variants |
Reference  |
|---|
   2.4.1.155 | A592G |
increased specific activity |
638555 |
| 2.4.1.155 | T555R |
increased specific activity |
638555 |
| 2.4.1.155 | V375L |
increased specific activity |
638555 |
| 2.4.1.155 | more |
N-acetylglucosaminyltransferase Va knockout mice, aberrant expression of several N-glycan structures, decrease in tumor progression |
703701 |
| 2.4.1.155 | more |
Mgat5 knockout mice, change in depression-like behaviour, decrease in immobility duration in tests of depression, no response to antidepressant treatment, altered social behavior in males |
703851 |
| 2.4.1.155 | more |
overexpression of GnT-V, change in glycosylation of receptor protein tyrosine phosphatase kappa, decrease of cell calcium-independent adhesion, increase of tyrosine phosphorylation level of beta-catenin |
704791 |
| 2.4.1.155 | more |
GnT-V overexpression induces an aberrant E-cadherin cellular localization and alters cell morphology, GnT-V increases the stability of the cadherin/catenin complex, GnT-V leads to a reduced intercellular adhesion of gastric cells, phenotype, overview |
721738 |
| 2.4.1.155 | more |
enzyme downregulation in cancer cells by specific shRNA expression |
735590 |
| 2.4.1.155 | more |
silencing of the enzyme by expression of short hairpin RNAs specific to Gnt-V in small cell lung cancer cell lines H1688 and H146 |
736094 |
| 2.4.1.155 | L188R |
site-directed mutagenesis, inactive mutant |
736192 |
