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EC Number Protein Variants Commentary Reference
Show all pathways known for 2.3.2.18Display the reaction diagram Show all sequences 2.3.2.18more in strains carrying mutations of FemA, femAB, or the femAX genes, the sorting reaction of surface proteins is significantly slowed. Strains carrying mutations in the fem genes display a decreased rate of surface protein precursor cleavage as compared with the wildtype strains, suggesting that the altered cross-bridges slow the anchoring of surface proteins 704390
Show all pathways known for 2.3.2.18Display the reaction diagram Show all sequences 2.3.2.18more the lysostaphin immunity factor Lif is able to complement lack of FemB by inserting serine for glycine in the side chain. Methicillin resistance, which depends on functional FemA and FemB, is not complemented by Lif suggesting that serine-substituted side-chains are a lesser substrate for penicillin-binding protein PBP2' in methicillin resistance 703744
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