EC Number |
Protein Variants |
Reference |
---|
2.3.1.299 | D210N |
site-directed mutagenesis, mutation in the Lag1p motif, the mutant shows highly reduced activity, but the mutation does not affect its fatty acid chain-length specificity |
754076 |
2.3.1.299 | D213N |
site-directed mutagenesis, mutation in the Lag1p motif, the mutant shows highly reduced activity, but the mutation does not affect its fatty acid chain-length specificity |
754076 |
2.3.1.299 | H182A/H183A |
site-directed mutagenesis |
752796 |
2.3.1.299 | H182A/H183A |
the mutant shows greatly reduced activity compared to the wild type enzyme |
752796 |
2.3.1.299 | H182D |
site-directed mutagenesis, mutation in the Lag1p motif, the mutant shows highly reduced activity, but the mutation does not affect its fatty acid chain-length specificity |
754076 |
2.3.1.299 | H183D |
site-directed mutagenesis, mutation in the Lag1p motif, the mutant shows highly reduced activity, but the mutation does not affect its fatty acid chain-length specificity |
754076 |
2.3.1.299 | H220D |
site-directed mutagenesis, mutation in the Lag1p motif, the mutant shows highly reduced activity, but the mutation does not affect its fatty acid chain-length specificity |
754076 |
2.3.1.299 | K220L |
site-directed mutagenesis, mutation in the Lag1p motif, the mutant enzyme is able to increase cellular C18 and C18:1 ceramide levels to a similar or slightly lesser extent than wild-type LASS1, the mutation does not affect the fatty acid chain-length specificity |
754076 |
2.3.1.299 | L189E |
site-directed mutagenesis, mutation in the Lag1p motif, the mutant shows highly reduced activity, but the mutation does not affect its fatty acid chain-length specificity |
754076 |
2.3.1.299 | L216E |
site-directed mutagenesis, mutation in the Lag1p motif, the mutant shows highly reduced activity, but the mutation does not affect its fatty acid chain-length specificity |
754076 |