EC Number   |
Protein Variants |
Reference |
|---|
   2.1.1.22 | C123A |
mutation in disulfide bridge, displays strongly enhanced activity compared to that of wild-type |
-, 755681 |
| 2.1.1.22 | C238A |
mutation in disulfide bridge, significantly reduces the activity |
755681 |
| 2.1.1.22 | D278A/T279A |
mutant barely displays any affinity to SAM |
755681 |
| 2.1.1.22 | E167A |
mutant barely displays any affinity to SAM |
-, 755681 |
| 2.1.1.22 | H309A |
about 40% of wild-type activity |
-, 755681 |
| 2.1.1.22 | L307F |
activity similar to wild-type |
755681 |
| 2.1.1.22 | N274A |
substantial reduction in expression level. Mutant barely displays any affinity to SAM |
755681 |
| 2.1.1.22 | Q108A |
mutant barely displays any affinity to SAM |
755681 |
| 2.1.1.22 | R111A |
mutant barely displays any affinity to SAM |
-, 755681 |
| 2.1.1.22 | S104A |
activity similar to wild-type |
755681 |
