EC Number   |
Protein Variants |
Reference |
|---|
    1.2.7.11 | D468A |
inactive with 2-oxoglutarate and pyruvate as substrate |
-, 739701 |
| 1.2.7.11 | K49I |
inactive with 2-oxoglutarate as substrate |
-, 739701 |
| 1.2.7.11 | T256A |
kcat and Km for 2-oxoglutarate are 33% and 51%, respectively, as compared with that of the wild-type enzyme |
-, 719399 |
| 1.2.7.11 | I255L |
kcat/Km for pyruvate is 11% of wild-type value, kcat/KM for 2-oxoglutarate is 21% of wild-type value |
719399 |
| 1.2.7.11 | P254G |
kcat/Km for pyruvate is 12% of wild-type value, kcat/KM for 2-oxoglutarate is 20% of wild-type value |
719399 |
| 1.2.7.11 | I255M |
kcat/Km for pyruvate is 13% of wild-type value, kcat/KM for 2-oxoglutarate is 2% of wild-type value |
719399 |
| 1.2.7.11 | I255V |
kcat/Km for pyruvate is 14% of wild-type value, kcat/KM for 2-oxoglutarate is 38% of wild-type value |
719399 |
| 1.2.7.11 | T256S |
kcat/Km for pyruvate is 15% of wild-type value, kcat/KM for 2-oxoglutarate is 92% of wild-type value |
-, 719399 |
| 1.2.7.11 | T256V |
kcat/Km for pyruvate is 17% of wild-type value, kcat/KM for 2-oxoglutarate is 68% of wild-type value |
-, 719399 |
| 1.2.7.11 | T256A |
kcat/Km for pyruvate is 21% of wild-type value, kcat/KM for 2-oxoglutarate is 15% of wild-type value |
-, 719399 |
