EC Number   |
Protein Variants |
Reference |
|---|
    1.2.1.13 | S188A |
affinity for NADPH is significantly decreased, decrease in the ratio of turnover number to Km-value in the NADPH-dependent reaction, significant expansion of the A4-tetramer |
656539 |
| 1.2.1.13 | T33A |
affinity for NADPH is significantly decreased, turnover-number for NADPH is lowered |
656539 |
| 1.2.1.13 | T33A/S188A |
affinity for NADPH is significantly decreased, turnover-number for NADPH is lowered |
656539 |
| 1.2.1.13 | A(plusCTE) |
chimeric mutant for testing the regulatory function of CTE |
676575 |
| 1.2.1.13 | E356Q/E357Q |
complete redox insensitivity is achieved in the double mutant |
689747 |
| 1.2.1.13 | more |
construction of hybrid enzymes between the glyceraldehyde-3-phosphate dehydrogenases from the mesophilic Methanobacterium bryantii and the thermophilic Methanothermus fervidus |
287989 |
| 1.2.1.13 | Y323S |
decrease of temperature of irreversible inactivation by 4.5°C |
287989 |
| 1.2.1.13 | B(minCTE) |
deletion mutant for testing the regulatory function of CTE |
676575 |
| 1.2.1.13 | Y123W |
increase of temperature of irreversible inactivation by 1.3°C |
287989 |
| 1.2.1.13 | K225A |
K225 is critical for binding of GAPDH to Siah1, an ubiquitin-E3-ligase, eliciting the translocation of GAPDH to the nucleus |
676851 |
