EC Number |
Protein Variants |
Reference |
---|
1.1.1.50 | F118A |
site-directed mutagenesis, mutation of a substrate binding residue, altered steroid recognition and kinetics compared to the wild-type enzyme |
655215 |
1.1.1.50 | F129A |
site-directed mutagenesis, mutation of a substrate binding residue, altered steroid recognition and kinetics compared to the wild-type enzyme, highly reduced activity |
655215 |
1.1.1.50 | L54A |
site-directed mutagenesis, mutation of a substrate binding residue, altered steroid recognition and kinetics compared to the wild-type enzyme |
655215 |
1.1.1.50 | N306A |
site-directed mutagenesis, mutation of a substrate binding residue, altered steroid recognition and kinetics compared to the wild-type enzyme |
655215 |
1.1.1.50 | T226A |
site-directed mutagenesis, mutation of a substrate binding residue, steroid recognition and kinetics are similar to the wild-type enzyme |
655215 |
1.1.1.50 | T24A |
site-directed mutagenesis, mutation of a substrate binding residue, steroid recognition and kinetics are similar to the wild-type enzyme |
655215 |
1.1.1.50 | W227A |
site-directed mutagenesis, mutation of a substrate binding residue, altered steroid recognition and kinetics compared to the wild-type enzyme, highly reduced activity and binding of progesterone |
655215 |
1.1.1.50 | Y310A |
site-directed mutagenesis, mutation of a substrate binding residue, altered steroid recognition and kinetics compared to the wild-type enzyme |
655215 |
1.1.1.50 | F118A |
site-directed mutagenesis, altered kinetic and catalytic efficiency compared to the wild-type enzyme |
656651 |
1.1.1.50 | L54A |
site-directed mutagenesis, altered kinetic and catalytic efficiency compared to the wild-type enzyme |
656651 |