BRENDA - Reference to 1.1.1.50; Id = 655215

F118A

site-directed mutagenesis, mutation of a substrate binding residue, altered steroid recognition and kinetics compared to the wild-type enzyme

Rattus norvegicus

F129A

site-directed mutagenesis, mutation of a substrate binding residue, altered steroid recognition and kinetics compared to the wild-type enzyme, highly reduced activity

Rattus norvegicus

L54A

site-directed mutagenesis, mutation of a substrate binding residue, altered steroid recognition and kinetics compared to the wild-type enzyme

Rattus norvegicus

N306A

site-directed mutagenesis, mutation of a substrate binding residue, altered steroid recognition and kinetics compared to the wild-type enzyme

Rattus norvegicus

T226A

site-directed mutagenesis, mutation of a substrate binding residue, steroid recognition and kinetics are similar to the wild-type enzyme

Rattus norvegicus

T24A

site-directed mutagenesis, mutation of a substrate binding residue, steroid recognition and kinetics are similar to the wild-type enzyme

Rattus norvegicus

W227A

site-directed mutagenesis, mutation of a substrate binding residue, altered steroid recognition and kinetics compared to the wild-type enzyme, highly reduced activity and binding of progesterone

Rattus norvegicus

Y310A

site-directed mutagenesis, mutation of a substrate binding residue, altered steroid recognition and kinetics compared to the wild-type enzyme

Rattus norvegicus

additional information

-

additional information

kinetics

Rattus norvegicus

additional information

Rattus norvegicus

enzyme plays a pivotal role in the inactivation of circulating steroid hormones

?

-

Rattus norvegicus

-

isozyme AKR1C9

-

a 3alpha-hydroxysteroid + NAD(P)+ = a 3-oxosteroid + NAD(P)H + H+

ordered bi bi kinetic mechanism, catalytic residues are Y55 and H117

Rattus norvegicus

liver

isozyme AKR1C9

Rattus norvegicus

-

additional information

enzyme plays a pivotal role in the inactivation of circulating steroid hormones

655215

Rattus norvegicus

?

-

additional information

wild-type enzyme recognizes only the 3-keto function of steroids, while the substrate binding residue-mutant enzymes show a broader substrate specificity and broader reaction spectra, overview, structure-function study on the basis of the crystal structure, modeling

655215

Rattus norvegicus

?

-

progesterone + NADPH

-

655215

Rattus norvegicus

?

-

?

testosterone + NADPH

substrate binding residues are T24, L54, Y55, H117, F118, F129, T226, W227, N306, and Y310

655215

Rattus norvegicus

?

-

?

More

structure-function study on the basis of the crystal structure, modeling

Rattus norvegicus

37

-

assay at

Rattus norvegicus

7

-

assay at

Rattus norvegicus

NADPH

-

Rattus norvegicus

NADPH

-

Rattus norvegicus

F118A

site-directed mutagenesis, mutation of a substrate binding residue, altered steroid recognition and kinetics compared to the wild-type enzyme

Rattus norvegicus

F129A

site-directed mutagenesis, mutation of a substrate binding residue, altered steroid recognition and kinetics compared to the wild-type enzyme, highly reduced activity

Rattus norvegicus

L54A

site-directed mutagenesis, mutation of a substrate binding residue, altered steroid recognition and kinetics compared to the wild-type enzyme

Rattus norvegicus

N306A

site-directed mutagenesis, mutation of a substrate binding residue, altered steroid recognition and kinetics compared to the wild-type enzyme

Rattus norvegicus

T226A

site-directed mutagenesis, mutation of a substrate binding residue, steroid recognition and kinetics are similar to the wild-type enzyme

Rattus norvegicus

T24A

site-directed mutagenesis, mutation of a substrate binding residue, steroid recognition and kinetics are similar to the wild-type enzyme

Rattus norvegicus

W227A

site-directed mutagenesis, mutation of a substrate binding residue, altered steroid recognition and kinetics compared to the wild-type enzyme, highly reduced activity and binding of progesterone

Rattus norvegicus

Y310A

site-directed mutagenesis, mutation of a substrate binding residue, altered steroid recognition and kinetics compared to the wild-type enzyme

Rattus norvegicus

additional information

-

additional information

kinetics

Rattus norvegicus

additional information

Rattus norvegicus

enzyme plays a pivotal role in the inactivation of circulating steroid hormones

?

-

liver

isozyme AKR1C9

Rattus norvegicus

-

additional information

enzyme plays a pivotal role in the inactivation of circulating steroid hormones

655215

Rattus norvegicus

?

-

additional information

wild-type enzyme recognizes only the 3-keto function of steroids, while the substrate binding residue-mutant enzymes show a broader substrate specificity and broader reaction spectra, overview, structure-function study on the basis of the crystal structure, modeling

655215

Rattus norvegicus

?

-

progesterone + NADPH

-

655215

Rattus norvegicus

?

-

?

testosterone + NADPH

substrate binding residues are T24, L54, Y55, H117, F118, F129, T226, W227, N306, and Y310

655215

Rattus norvegicus

?

-

?

More

structure-function study on the basis of the crystal structure, modeling

Rattus norvegicus

37

-

assay at

Rattus norvegicus

7

-

assay at

Rattus norvegicus

740017

Zhang

Human 3alpha-hydroxysteroid de ...

Homo sapiens

Biochem. J.

473

1037-1046

2016

-

1

-

1

-

1

-

2

-

1

-

2

-

2

1

-

1

-

2

-

1

-

2

-

740802

Yang

One step affinity recovery of ...

Comamonas testosteroni, Comamonas testosteroni ATCC 11996

J. Chromatogr. B

991

79-84

2015

-

1

-

2

4

-

5

-

1

-

2

-

6

1

-

1

-

2

-

1

2

-

2

4

-

1

-

2

-

6

1

-

1

-

741098

Yunes

Progesterone exerts a neuromod ...

Rattus norvegicus, Rattus norvegicus Sprague-Dawley

Parkinsons Dis.

2015

431690

2015

-

2

-

2

-

3

-

2

-

1

-

1

-

2

-

2

-

2

-

3

-

2

-

1

-

1

-

1

-

741361

Chen

Expression, purification and f ...

Pseudomonas aeruginosa

Protein Expr. Purif.

115

102-108

2015

-

1

-

3

1

-

6

1

-

1

-

1

-

2

1

-

1

-

2

-

1

2

-

3

-

1

-

6

1

-

1

-

2

1

-

1

-

1

-

738928

Zhang

Human 3-alpha hydroxysteroid d ...

Homo sapiens

J. Steroid Biochem. Mol. Biol.

141

135-143

2014

-

1

-

4

-

1

-

1

-

1

-

2

-

1

-

4

1

-

2

-

1

2

1

-

4

-

1

-

1

-

2

-

1

-

4

1

-

3

-

4

741274

Hwang

The catalytic roles of P185 an ...

Comamonas testosteroni

PLoS ONE

8

e63594

2013

-

1

-

6

-

1

-

1

-

1

-

1

-

2

1

-

1

-

2

-

1

2

-

6

-

1

-

1

-

1

-

2

1

-

1

-

3

-

726505

Mundaca

Enzyme biosensor for androster ...

Comamonas testosteroni

Talanta

99

697-702

2012

-

1

-

1

-

1

-

1

-

1

-

711310

Chang

Contributions of active site r ...

Comamonas testosteroni

Biochim. Biophys. Acta

1804

235-241

2010

-

1

-

3

-

1

11

-

1

-

2

-

1

8

-

4

-

1

2

-

6

-

4

2

8

14

-

2

-

695886

Hwang

Interactions across the interf ...

Comamonas testosteroni

Arch. Biochem. Biophys.

490

36-41

2009

-

1

-

3

-

5

-

1

-

1

-

1

-

1

-

2

-

5

-

1

-

3

-

5

-

1

-

1

-

2

-

5

-

696459

Chang

Role of S114 in the NADH-induc ...

Comamonas testosteroni

Biochim. Biophys. Acta

1794

1459-1466

2009

-

1

-

1

-

1

6

-

1

-

1

-

2

-

2

-

2

-

1

2

-

1

-

1

2

6

-

1

-

2

-

2

-

4

696786

Hidai

The Del1 deposition domain can ...

Homo sapiens, Mus musculus

Bioprocess Biosyst. Eng.

32

569-573

2009

-

1

-

2

-

2

-

1

-

1

-

1

-

1

-

2

-

1

-

1

-

697268

Xiong

3alpha-Hydroxysteroid dehydrog ...

Comamonas testosteroni

Chem. Biol. Interact.

178

206-210

2009

1

-

1

-

1

-

697270

Xiong

Cis- and trans-regulatory elem ...

Comamonas testosteroni

Chem. Biol. Interact.

178

215-220

2009

-

2

-

2

-

2

-

1

-

685529

Uwai

Electronic effects of para-sub ...

Rattus norvegicus

Bioorg. Med. Chem.

16

1084-1089

2008

-

1

-

1

-

1

-

8

-

1

-

1

-

1

-

1

-

1

-

1

-

8

-

1

-

1

-

688137

Azzarello

Tissue distribution of human A ...

Homo sapiens, Rattus norvegicus

J. Histochem. Cytochem.

56

853-861

2008

-

1

-

6

-

2

-

2

-

14

-

2

1

-

1

-

6

-

2

-

14

-

2

1

-

688983

Wang

AKR1C2 and AKR1C3 mediated pro ...

Homo sapiens

Mol. Cell. Endocrinol.

289

60-66

2008

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

689076

Stayrook

Regulation of human 3 alpha-hy ...

Homo sapiens

Mol. Pharmacol.

73

607-612

2008

1

-

1

-

1

-

2

-

2

-

1

-

1

-

1

-

1

-

2

-

1

-

689169

Meyer

The biological activity of 3al ...

Rattus norvegicus

Neurobiol. Dis.

30

30-41

2008

-

1

-

1

-

1

-

2

-

2

1

-

2

-

1

-

2

-

1

-

2

-

2

1

-

684676

Sanai

Rat NAD+-dependent 3alpha-hydr ...

Rattus norvegicus

Arch. Biochem. Biophys.

464

122-129

2007

-

1

-

3

-

1

9

2

-

2

-

1

-

1

-

2

-

31

1

-

9

1

-

4

1

-

1

4

-

3

-

1

9

2

-

2

-

1

-

2

-

31

1

-

9

1

-

687635

Cooper

Elucidation of a complete kine ...

Rattus norvegicus

J. Biol. Chem.

282

33484-33493

2007

-

3

-

1

-

1

-

1

-

1

-

1

-

1

-

2

1

-

2

-

2

-

3

-

1

-

1

-

1

-

1

-

2

1

-

687642

Chang

Mechanism of proton transfer i ...

Comamonas testosteroni

J. Biol. Chem.

282

34306-34314

2007

-

1

-

2

-

3

-

1

-

1

-

1

-

1

-

2

-

1

-

1

-

2

-

1

2

-

2

-

3

-

1

-

1

-

1

-

2

-

1

-

1

-

687870

Hoffmann

Understanding oligomerization ...

Comamonas testosteroni

J. Biotechnol.

129

131-139

2007

-

1

-

1

-

1

-

1

-

2

-

1

-

1

-

1

-

2

-

671112

Kataoka

Crystallization and preliminar ...

Pseudomonas sp., Pseudomonas sp. B-0831

Acta Crystallogr. Sect. F

62

569-571

2006

-

1

-

1

-

6

-

1

-

2

1

-

1

-

1

-

1

-

1

-

2

1

-

672088

Jin

Multiple steps determine the o ...

Homo sapiens

Biochemistry

45

13054-13063

2006

-

1

-

3

-

1

-

1

-

1

-

1

-

3

-

1

-

2

1

-

2

-

1

2

-

3

-

1

-

1

-

1

-

3

-

1

-

2

1

-

673349

Papari-Zareei

Arginine 276 controls the dire ...

Rattus norvegicus

Endocrinology

147

1591-1597

2006

-

1

-

3

-

1

-

1

-

3

-

1

-

1

-

2

-

1

-

1

-

3

-

1

-

1

-

1

-

2

-

674674

Nakamura

Apo- and holo-structures of 3a ...

Pseudomonas sp., Pseudomonas sp. B-0831

J. Biol. Chem.

281

31876-31884

2006

-

1

-

1

2

-

2

-

2

-

1

-

1

-

1

2

-

2

-

674981

Okochi

Enhanced activity of 3alpha-hy ...

Comamonas testosteroni

J. Biotechnol.

128

376-382

2006

3

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

2

-

3

1

-

2

-

1

-

1

-

1

-

1

-

1

-

1

-

675595

Steckelbroeck

Tibolone metabolism in human l ...

Homo sapiens

J. Pharmacol. Exp. Ther.

316

1300-1309

2006

-

3

-

2

-

1

-

1

-

3

1

-

3

-

1

-

1

-

1

-

2

-

1

-

2

3

-

2

-

1

-

3

1

-

3

-

1

-

1

-

676812

Yee

Fluorogenic metabolic probes f ...

Homo sapiens

Proc. Natl. Acad. Sci. USA

103

13304-13309

2006

-

1

-

6

2

-

2

-

2

-

1

-

4

-

1

-

5

-

1

-

5

6

-

2

-

2

-

1

-

4

-

669389

Hwang

Mechanistic roles of Ser-114, ...

Comamonas testosteroni

J. Biol. Chem.

280

3522-3528

2005

-

1

-

5

-

7

-

1

-

1

-

1

-

1

-

2

1

-

6

1

-

2

-

1

2

-

5

-

7

-

1

-

1

-

1

-

2

1

-

6

1

-

654186

Ueda

Kinetic study of the enzymatic ...

Pseudomonas sp., Pseudomonas sp. B-0831

Anal. Biochem.

332

84-89

2004

-

1

-

1

-

6

-

1

-

1

-

1

-

4

-

1

4

-

1

-

1

-

1

-

655790

Yee

New tools for molecular imagin ...

Comamonas testosteroni, Homo sapiens, Rattus norvegicus

J. Am. Chem. Soc.

126

2282-2283

2004

-

2

-

1

-

3

-

3

-

4

-

2

-

6

-

6

-

2

-

1

-

3

-

4

-

2

-

656200

Steckelbroeck

Human cytosolic 3alpha-hydroxy ...

Homo sapiens

J. Biol. Chem.

279

10784-10795

2004

-

1

-

2

-

1

-

4

-

2

-

1

-

1

4

-

7

-

1

-

4

1

-

3

-

1

3

-

2

-

1

-

4

-

1

-

1

4

-

7

-

1

-

4

1

-

656300

Ueda

-

Steady-state kinetic propertie ...

Pseudomonas sp., Pseudomonas sp. B-0831

J. Biol. Macromol.

4

23-28

2004

-

11

-

6

-

15

-

1

-

10

1

-

5

-

5

-

11

-

15

-

1

-

10

1

-

656787

Penning

Structure-function of human 3a ...

Homo sapiens

Mol. Cell. Endocrinol.

215

63-72

2004

-

1

-

1

12

-

3

-

3

-

1

-

5

1

-

13

-

1

-

14

1

-

1

-

1

-

12

-

3

-

5

1

-

13

-

1

-

14

1

-

656838

Steckelbroeck

Tibolone is metabolized by the ...

Homo sapiens

Mol. Pharmacol.

66

1702-1711

2004

-

1

-

2

1

-

1

-

2

-

1

-

1

6

-

7

-

1

-

6

1

-

4

-

1

4

-

2

-

1

-

1

-

1

-

1

6

-

7

-

1

-

6

1

-

655214

Jin

Examination of the differences ...

Homo sapiens, Rattus norvegicus

Chem. Biol. Interact.

143-144

383-392

2003

-

1

2

-

1

-

4

-

4

-

2

-

2

-

7

1

-

2

-

4

-

1

4

2

-

1

-

4

-

2

-

7

1

-

2

-

655215

Heredia

Steroid-binding site residues ...

Rattus norvegicus

Chem. Biol. Interact.

143-144

393-400

2003

-

8

-

1

-

1

-

1

-

1

-

1

-

4

1

-

1

-

1

-

1

-

8

-

1

-

1

-

1

-

4

1

-

1

-

655348

Rizner

Human type 3 3alpha-hydroxyste ...

Homo sapiens

Endocrinology

144

2922-2932

2003

-

1

-

1

3

-

1

-

2

-

1

-

2

-

1

-

3

1

-

4

-

1

4

-

1

-

3

-

1

-

1

-

2

-

1

-

3

1

-

656651

Penning

Structure-function relationshi ...

Homo sapiens, Rattus norvegicus

J. Steroid Biochem. Mol. Biol.

85

247-255

2003

-

2

1

7

-

2

-

2

-

2

-

1

-

8

2

-

9

-

1

-

2

1

7

-

2

-

2

-

2

-

1

-

8

2

-

9

-

654626

Trauger

Kinetics of allopregnanolone f ...

Homo sapiens

Biochemistry

41

13451-13459

2002

2

-

1

-

1

6

-

1

-

2

-

1

-

3

-

1

-

5

1

-

1

5

-

2

-

1

-

1

5

6

-

1

-

1

-

3

-

1

-

5

1

-

654924

Usami

Substrate specificity of human ...

Homo sapiens

Biol. Pharm. Bull.

25

441-445

2002

-

8

4

-

1

-

1

-

1

-

4

-

1

-

4

1

-

1

10

-

1

-

8

10

4

-

1

-

4

-

1

-

4

1

-

656642

Gao

Hypothalamic 5alpha-reductase ...

Rattus norvegicus

J. Steroid Biochem. Mol. Biol.

80

91-98

2002

-

3

-

1

-

1

-

4

-

1

-

1

-

2

-

2

-

3

-

1

-

4

-

1

-

1

-

656648

Lou

Intestinal and hepatic microso ...

Ictalurus punctatus

J. Steroid Biochem. Mol. Biol.

82

413-424

2002

-

2

-

3

-

5

3

-

1

-

1

-

1

-

1

-

1

-

2

-

5

3

-

1

-

1

-

1

-

389541

Chetyrkin

Characterization of a novel ty ...

Homo sapiens

J. Biol. Chem.

276

22278-22286

2001

-

1

-

3

1

-

1

-

1

-

1

2

-

7

-

3

-

1

3

-

3

1

-

1

-

1

2

-

7

-

389550

Jin

Crystal structure of human typ ...

Homo sapiens

Biochemistry

40

10161-10168

2001

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

389551

Zhu

Crystallization and preliminar ...

Homo sapiens

Acta Crystallogr. Sect. D

57

589-591

2001

-

1

-

1

-

2

-

1

-

2

-

1

-

1

-

1

-

2

-

389546

Maser

Functional expression, purific ...

Comamonas testosteroni

Biochem. Biophys. Res. Commun.

272

622-628

2000

-

1

-

5

-

2

-

1

-

1

-

5

-

12

1

-

1

-

1

-

5

-

2

-

1

-

5

-

12

1

-

389552

Gao

Purification and properties of ...

Pseudomonas sp.

Ann. N. Y. Acad. Sci.

864

383-392

1998

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

389540

Biswas

Expression cloning and charact ...

Homo sapiens, Rattus norvegicus

J. Biol. Chem.

272

15959-15966

1997

-

2

-

6

-

2

-

2

-

4

2

-

16

-

5

-

2

-

6

-

2

-

4

2

-

16

-

5

-

389547

Lin

Expression and characterizatio ...

Homo sapiens

Mol. Endocrinol.

11

1971-1984

1997

-

1

-

10

-

1

-

4

-

1

-

12

10

-

13

-

11

-

2

-

1

2

-

10

-

1

-

1

-

12

10

-

13

-

11

-

389548

Adachi

-

Purification and properties of ...

Pseudomonas putida

Biosci. Biotechnol. Biochem.

61

131-137

1997

-

1

-

1

-

3

1

-

1

-

1

-

1

-

1

2

9

1

-

1

-

1

-

1

-

1

-

1

-

3

1

-

1

-

1

-

1

2

9

1

-

1

-

1

-

1

-

389557

Li

Regional distribution of cytos ...

Rattus norvegicus

J. Steroid Biochem. Mol. Biol.

60

311-318

1997

-

2

-

3

-

2

-

1

-

6

-

2

-

2

-

2

-

3

-

1

-

6

-

389563

Lindemann

-

Biosynthesis of pregnane deriv ...

Digitalis lanata

Phytochemistry

46

507-513

1997

-

2

-

1

-

2

1

-

2

-

2

-

2

1

-

2

-

389562

Stuhlemmer

-

Cardenolide formation and acti ...

Digitalis lanata

Plant Physiol. Biochem.

34

85-91

1996

-

1

-

1

-

1

-

1

-

3

2

-

3

-

1

-

1

-

1

-

1

-

1

-

1

-

3

2

-

3

-

1

-

347986

Mallonee

Expression in Escherichia coli ...

Eubacterium sp., Eubacterium sp. VPI 12708

Curr. Microbiol.

30

259-263

1995

-

1

-

1

-

14

-

1

-

2

1

-

2

-

1

2

-

1

-

1

-

2

1

-

389560

Seitz

-

Enzymes in cardenolide-accumul ...

Digitalis purpurea

Plant Cell Tissue Organ Cult.

38

337-344

1994

-

4

2

-

2

-

1

-

1

-

3

-

3

-

3

-

4

2

-

2

-

1

-

3

-

389559

Karavolas

Changes in pituitary, hypothal ...

Rattus norvegicus

J. Steroid Biochem. Mol. Biol.

44

299-303

1993

-

2

-

3

-

1

-

3

-

5

-

2

-

2

-

2

-

3

-

3

-

5

-

389545

Iyer

Purification and properties of ...

Homo sapiens

J. Steroid Biochem. Mol. Biol.

43

343-349

1992

-

1

4

1

2

-

1

-

2

-

1

-

2

-

6

1

-

1

-

1

-

1

-

1

-

4

-

1

2

-

1

-

1

-

2

-

6

1

-

1

-

389549

Nanjo

Characterization of bovine liv ...

Bos taurus

Int. J. Biochem.

24

815-820

1992

-

7

-

2

-

1

-

3

-

1

-

1

-

13

1

-

2

-

2

-

7

-

2

-

1

-

1

-

1

-

13

1

-

389554

Pawlowski

Isolation and partial characte ...

Rattus norvegicus

Agents Actions

34

289-293

1991

-

1

-

2

-

1

-

3

-

2

-

1

-

1

-

2

-

1

-

2

-

1

-

389544

Campbell

Purification of the NADPH:5alp ...

Rattus norvegicus

J. Steroid Biochem. Mol. Biol.

37

215-222

1990

-

4

2

-

1

-

2

-

1

-

2

-

2

1

-

1

-

1

-

4

2

-

1

-

1

-

2

-

2

1

-

389555

Sugimoto

In vitro metabolism of testost ...

Gallus gallus

J. Steroid Biochem.

35

271-279

1990

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

587068

Morikawa

Purification and characterizat ...

Gallus gallus

J. Steroid Biochem. Mol. Biol.

37

569-574

1990

-

1

-

1

2

-

1

-

2

-

1

-

3

1

-

1

-

1

-

1

-

1

2

-

1

-

1

-

3

1

-

389527

Hara

Purification and characterizat ...

Mus musculus

J. Biochem.

103

1027-1034

1988

-

1

28

11

2

-

2

-

3

-

1

-

2

1

12

1

-

1

-

3

-

1

-

28

-

11

2

-

2

-

1

-

2

1

12

1

-

1

-

3

-

389556

Stolz

3alpha-hydroxysteroid dehydrog ...

Rattus norvegicus

J. Clin. Invest.

79

427-434

1987

-

1

-

2

-

1

-

2

-

1

-

3

-

2

-

1

-

1

-

1

-

1

-

2

-

1

-

1

-

3

-

2

-

1

-

349245

Boutin

Rat liver microsomal 3alpha-hy ...

Rattus norvegicus

Biochem. Biophys. Res. Commun.

135

795-801

1986

-

1

-

1

-

2

-

1

-

2

1

-

1

-

1

-

1

-

2

1

-

389525

Penning

Purification and properties of ...

Rattus norvegicus

J. Biol. Chem.

260

15266-15272

1985

-

9

1

2

-

2

1

-

2

-

1

-

2

1

3

1

-

9

-

1

2

-

2

1

-

1

-

2

1

3

1

-

389526

Ikeda

Purification and characterizat ...

Rattus norvegicus

Hoppe-Seyler's Z. Physiol. Chem.

365

377-391

1984

-

2

1

2

-

1

-

2

-

1

-

2

-

1

5

-

2

-

2

-

1

2

-

1

-

1

-

2

-

1

5

-

2

-

389561

Bertics

Potent inhibition of the hypot ...

Rattus norvegicus

J. Biol. Chem.

259

107-111

1984

-

1

-

3

-

1

-

1

-

1

-

1

-

2

-

2

-

1

-

3

-

1

-

1

-

1

-

389528

Hastings

Kinetic properties of the solu ...

Rattus norvegicus

J. Steroid Biochem.

14

705-711

1981

-

1

2

1

-

1

-

2

-

4

-

4

-

1

-

2

1

-

1

-

4

-

4

-

389558

Krause

Subcellular location of hypoth ...

Rattus norvegicus

J. Steroid Biochem.

13

271-280

1980

-

2

-

2

-

1

-

1

-

4

-

2

-

2

-

2

-

2

-

1

-

4

-

347740

MacDonald

Bile salt 3alpha- and 12alpha- ...

Eggerthella lenta

Appl. Environ. Microbiol.

37

992-1000

1979

-

1

-

1

-

1

-

389522

Uwajima

-

Properties of crystalline 3alp ...

Pseudomonas putida

Agric. Biol. Chem.

43

1521-1528

1979

-

1

-

1

2

-

1

-

1

-

1

12

1

-

1

-

1

-

1

-

1

-

1

-

2

-

2

-

1

-

1

12

1

-

1

-

1

-

1

-

389523

Uwajima

-

Production, purification and c ...

Pseudomonas putida

Agric. Biol. Chem.

42

1577-1583

1978

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

347742

Mahony

Bile salt degradation by nonfe ...

Asaccharospora irregularis

Appl. Environ. Microbiol.

34

419-423

1977

-

1

-

347743

MacDonald

NAD-dependent 3alpha- and 12al ...

Eggerthella lenta

Biochim. Biophys. Acta

489

466-476

1977

-

3

-

1

-

1

7

-

1

-

1

-

3

-

1

7

-

1

-

1

-

389529

Jacobi

Characterization of the 3alpha ...

Canis lupus familiaris

J. Steroid Biochem.

8

719-723

1977

-

17

1

2

-

1

-

1

-

2

-

17

-

1

2

-

1

-

2

-

389531

Inano

Prostate 3alpha-hydroxysteroid ...

Rattus norvegicus

J. Steroid Biochem.

8

41-46

1977

-

1

-

1

-

1

-

1

-

1

-

2

-

1

-

1

-

1

-

1

-

1

-

1

-

2

-

1

-

1

-

389532

Golf

Solubilization and purificatio ...

Rattus norvegicus

Hoppe-Seyler's Z. Physiol. Chem.

357

35-40

1976

-

1

-

1

-

1

-

1

-

1

3

-

1

-

1

-

1

-

1

3

-

389530

Nimrod

Separation and characterizatio ...

Rattus norvegicus

J. Steroid Biochem.

6

1205-1209

1975

-

2

1

-

1

-

1

-

2

-

2

1

-

1

-

2

-

389533

Skalhegg

3alpha-Hydroxysteroid dehydrog ...

Comamonas testosteroni

Eur. J. Biochem.

50

603-609

1975

-

1

-

2

-

1

-

1

-

1

-

1

-

389524

Skalhegg

On the 3alpha-hydroxysteroid d ...

Comamonas testosteroni

Eur. J. Biochem.

46

117-125

1974

-

2

-

2

-

2

-

2

-

2

-

389536

Squire

Physical and chemical characte ...

Comamonas testosteroni

Biochim. Biophys. Acta

89

409-421

1964

-

1

-

1

-

1

-

1

-

1

-

389534

Jarabak

Stereospecificity of hydrogen ...

Comamonas testosteroni

J. Biol. Chem.

235

2147-2151

1960

-

1

-

1

-

1

-

Steroid-binding site residues dictate optimal substrate positioning in rat 3alpha-hydroxysteroid dehydrogenase (3alpha-HSD or AKR1C9)

Data extracted from this reference: