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EC Number
Protein Variants
Commentary
Reference
4.1.3.16
Y140F
122% of wild-type activity
723542
4.1.3.16
S198T
18% of wild-type activity
723542
4.1.3.16
S77T
2% of wild-type activity
723542
4.1.3.16
S77V
2% of wild-type activity
723542
4.1.3.16
N78A
20% of wild-type activity
723542
4.1.3.16
N78Q
4% of wild-type activity
723542
4.1.3.16
N78T
45% of wild-type activity
723542
4.1.3.16
S77A
5% of wild-type activity
723542
4.1.3.16
S198A
9% of wild-type activity
723542
4.1.3.16
R255X
a truncation of 71 residues from the C-terminus associated with Primary Hyperoxaluria type 3. Mutant is quite unstable, has a tendency to aggregate, and retains no measurable activity
721727
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