EC Number   |
Protein Variants |
Reference |
|---|
   3.4.22.B79 | C525S |
mutant is active and processed normally |
29849 |
| 3.4.22.B79 | G17V |
mutation causes an increase in infectous viral titer, variants become cytopathic for both BHK-21 and Vero cells |
732418 |
| 3.4.22.B79 | G577R |
temperature-sensitive in vivo and in vitro |
679819 |
| 3.4.22.B79 | G8063V |
mutation blocks P2/3 cleavage during P123 processing |
699903 |
| 3.4.22.B79 | H548A |
inactive |
679819 |
| 3.4.22.B79 | H558A |
mutation in C-terminal protease domain, abolishes catalytic activity, and is lethal |
29849 |
| 3.4.22.B79 | H558Q |
mutation in C-terminal protease domain, abolishes catalytic activity, and is lethal |
29849 |
| 3.4.22.B79 | H558Y |
mutation in C-terminal protease domain, abolishes catalytic activity, and is lethal |
29849 |
| 3.4.22.B79 | H619A |
mutant is active and processed normally |
29849 |
| 3.4.22.B79 | H701A |
mutant is active and processed normally |
29849 |
