EC Number |
Protein Variants |
Reference |
---|
3.4.21.42 | Q340A |
similar to wild-type |
669727 |
3.4.21.42 | Q340D |
complement component C4 cleavage activity below 50% compared to wild-type, complement component C2 cleavage activity similar to wild-type |
669727 |
3.4.21.42 | Q340D/D343E |
complement component C4 cleavage activity below 50% compared to wild-type, complement component C2 cleavage activity similar to wild-type |
669727 |
3.4.21.42 | Q340E |
activation by complement component C1r is impaired, enhanced glycosylation at N391 |
669727 |
3.4.21.42 | Q340E/D343N |
complement component C4 cleavage activity below 50% compared to wild-type, complement component C2 cleavage activity similar to wild-type |
669727 |
3.4.21.42 | Q340E/N391Q |
similar to wild-type |
669727 |
3.4.21.42 | Q340K |
complement component C4 cleavage activity below 50% compared to wild-type, complement component C2 cleavage activity similar to wild-type |
669727 |
3.4.21.42 | Q340K/D343N |
complement component C4 cleavage activity below 50% compared to wild-type, complement component C2 cleavage activity similar to wild-type |
669727 |
3.4.21.42 | Q340K/P341I |
complement component C4 cleavage activity below 50% compared to wild-type, complement component C2 cleavage activity similar to wild-type |
669727 |
3.4.21.42 | Q340K/P341I/V342K |
complement component C4 cleavage activity below 50% compared to wild-type, complement component C2 cleavage activity similar to wild-type |
669727 |