EC Number |
Protein Variants |
Reference |
---|
2.6.1.B21 | Y31F/H86F/Y88F |
site-directed mutagenesis, variant M2-3 shows significant activity toward (R)-PEA and retains 34% of the native DATA activity |
758564 |
2.6.1.B21 | Y31F/H86F/Y88F/H100L/S180A/T242I |
site-directed mutagenesis, variant M2-6 shows almost complete depletion of the native DATA activity but high activity toward (R)-phenylethylamine ((R)-PEA) and has a specific activity of 326 milliunits/mg in the conversion of (R)-PEA and pyruvate to acetophenone and D-alanine |
758564 |
2.6.1.B21 | Y31F/H86F/Y88F/S180A/T242I |
site-directed mutagenesis, variant M2-5 shows significant activity toward (R)-PEA and partially retains native DATA activity |
758564 |
2.6.1.B21 | Y59W/T231A |
site-directed mutagenesis, inactive mutant |
759050 |
2.6.1.B21 | Y59W/Y87F/T231A |
site-directed mutagenesis, inactive mutant |
759050 |
2.6.1.B21 | Y59W/Y87L/T231A |
site-directed mutagenesis, specific and enantioimeric conversion of 2,2-dimethyl-1-phenylpropan-1-amine compared to wild-type |
759050 |
2.6.1.B21 | Y59W/Y87L/T231A/G429A |
site-directed mutagenesis, specific and enantioimeric conversion of 2,2-dimethyl-1-phenylpropan-1-amine compared to wild-type |
759050 |
2.6.1.B21 | Y59W/Y87L/T231A/L382M |
site-directed mutagenesis, specific and enantioimeric conversion of 2,2-dimethyl-1-phenylpropan-1-amine compared to wild-type |
759050 |
2.6.1.B21 | Y59W/Y87L/T231A/L382M/G429A |
site-directed mutagenesis, specific and enantioimeric conversion of 2,2-dimethyl-1-phenylpropan-1-amine compared to wild-type |
759050 |
2.6.1.B21 | Y59W/Y87L/Y152F/T231A/L382M/G429A |
site-directed mutagenesis, specific and enantioimeric conversion of 2,2-dimethyl-1-phenylpropan-1-amine compared to wild-type |
759050 |