EC Number   |
Protein Variants |
Reference |
|---|
    2.5.1.22 | more |
the loss-of-function mutant of gene ACAULIS5 shows a severe defect in stem elongation, isolation of a T-DNA insertion mutant of gene SPMS, i.e. spms-1, showing decreased spermine levels but no obvious phenotypic alterations, an acl5-spms-1 double mutant contains no spermine but is fully viable as the wild-type and shows no phenotypic alterations under normal growth conditions, overview |
658727 |
| 2.5.1.22 | more |
yeast does not require spermine synthase since mutants in which this enzyme is deleted are viable and grow at a normal rate |
708060 |
| 2.5.1.22 | P112L |
the mutation is associated with the Snyder-Robinson syndrome |
738421 |
| 2.5.1.22 | S165D/L175E/T178H/C206R |
the mutant shows increased activity compared to the wild type enzyme |
739393 |
| 2.5.1.22 | V132G |
naturally occuring missense mutation involved in Snyder-Robinson Syndrome, the mutation affects dimer and monomer stability and perturb the hydrogen bond network of the functionally important amino acids |
723531 |
| 2.5.1.22 | V132G |
point mutation, leads to a large loss of spermine synthase activity, an inability to form dimers |
708060 |
