EC Number |
Protein Variants |
Reference |
---|
2.3.1.129 | H144A |
lower specific activity than wild-type |
486258 |
2.3.1.129 | H144N |
lower specific activity than wild-type |
486258 |
2.3.1.129 | H160A |
lower specific activity than wild-type |
486258 |
2.3.1.129 | H160F |
lower specific activity than wild-type |
486258 |
2.3.1.129 | H53I/D59I |
residue tolerance in the beta-helical domain: mutation is tolerated |
706784 |
2.3.1.129 | H53V/D59V |
residue tolerance in the beta-helical domain: mutation is tolerated |
706784 |
2.3.1.129 | I20R |
mutation in the hydrophobic residue in the beta-helical core located in rung 2: LpxA is active |
706784 |
2.3.1.129 | I2R |
mutation in the hydrophobic residue in the beta-helical core located in rung 1: LpxA is active |
706784 |
2.3.1.129 | I38R |
mutation in the hydrophobic residue in the beta-helical core located in rung 3: LpxA is partially active |
706784 |
2.3.1.129 | I56A |
mutation in the hydrophobic core of the beta-helical domain: LpxA activity is not significantly affected compared to wild-type |
706784 |