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EC Number
Protein Variants
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2.3.1.129
V111R
mutation in the hydrophobic residue in the beta-helical core located in rung 6: LpxA is inactive
706784
2.3.1.129
V129R
mutation in the hydrophobic residue in the beta-helical core located in rung 7: LpxA is inactive
706784
2.3.1.129
Y66F/Y77F/Y219F/Y223F/Y243H
all but one tyrosine residues are mutated. Mutant shows growth similar to wild-type after introduction into Escherichia coli strain SM101 bearing a defective LpxA gene (G189S), and under novobiocin supplementation
706784
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