EC Number   |
Protein Variants |
Reference  |
|---|
   1.20.1.1 | K76R |
significant increase in Km for both substrates |
-, 658120 |
| 1.20.1.1 | R237H |
almost complete loss of activity |
658120 |
| 1.20.1.1 | R237K |
significant increase in Km for both substrates |
658120 |
| 1.20.1.1 | R237L |
almost complete loss of activity |
658120 |
| 1.20.1.1 | R237Q |
almost complete loss of activity |
658120 |
| 1.20.1.1 | H292F |
no activity, NAD+ binding is abolished |
-, 658259 |
| 1.20.1.1 | H292K |
no activity, NAD+ binding is abolished |
-, 658259 |
| 1.20.1.1 | H292N |
no activity, NAD+ binding is abolished |
-, 658259 |
| 1.20.1.1 | H292Q |
no activity, NAD+ binding is abolished |
658259 |
| 1.20.1.1 | R237K |
strong increase in Km for both substrates, reduced Vmax |
-, 658259 |
