EC Number   |
Protein Variants |
Reference |
|---|
   1.14.15.8 | G397P |
the mutant exhibits 2% of the wild-type activity, Vmax/Km for progesterone is 51.7fold lower than wild-type value |
697323 |
| 1.14.15.8 | I86T |
Vmax/Km for progesterone is 2fold higher than wild-type value |
697323 |
| 1.14.15.8 | K27R/I71T/I215T |
Vmax/Km for progesterone is 2.5fold higher than wild-type value |
697323 |
| 1.14.15.8 | more |
construction of a CYP106A2 knockout strain |
-, 711747 |
| 1.14.15.8 | more |
modelling of CYP106A2 and site-directed mutagenesis of the protein to check the accuracy of the computer-derived model of CYP106A2 |
696142 |
| 1.14.15.8 | more |
recombinant reconstitution of the whole cell conversion of 11-keto-beta-boswellic acid in Bacillus megaterium strain MS941 by coexpression of heterologous redox chain of the P450, bovine adrenodoxin reductase, and bovine adrenodoxin, as well as a a NADPH-regenerating system |
-, 724061 |
| 1.14.15.8 | Q398S |
Vmax/Km for progesterone is 5fold lower than wild-type value |
697323 |
| 1.14.15.8 | S394I |
Vmax/Km for progesterone is 7.5fold lower than wild-type value |
697323 |
| 1.14.15.8 | S72A/V73I |
mutant does not show a better stability in the crystallization process than the wild-type protein |
696142 |
| 1.14.15.8 | T248V |
specificity for 15beta-hydroxylation is improved |
699068 |
