EC Number |
Protein Variants |
Reference |
---|
4.2.1.108 | Y52A |
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme |
749081 |
4.2.1.108 | Y85A |
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme |
749081 |
4.2.1.108 | Y85F |
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme |
749081 |
4.2.1.108 | Y85W |
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme |
749081 |
4.2.1.108 | D91E |
site-directed mutagenesis, the mutant shows similar activity as the wild-type enzyme |
749081 |
4.2.1.108 | H51A |
site-directed mutagenesis, the mutant shows similar activity as the wild-type enzyme |
749081 |
4.2.1.108 | T41A |
site-directed mutagenesis, the mutant shows similar activity as the wild-type enzyme |
749081 |
4.2.1.108 | more |
structure-guided site-directed mutagenesis is used targeting amino acid residues that are evolutionarily highly conserved among the extended EctC protein family, including those forming the presumptive iron-binding site |
-, 749081 |