EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   3.4.23.49 | Anthrax |
1644824 |
Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen. |
causal interaction
unassigned |
1
0 |
| 3.4.23.49 | Anthrax |
29224733 |
Validated MALDI-TOF-MS method for anthrax lethal factor provides early diagnosis and evaluation of therapeutics. |
diagnostic usage
therapeutic application
unassigned |
4
1
0 |
| 3.4.23.49 | Bernard-Soulier Syndrome |
10946090 |
Responses to aggregating agents after cleavage of GPIb of human platelets by the O-sialoglycoprotein endoprotease from Pasteurella haemolytica- potential surrogates for Bernard-Soulier platelets? |
therapeutic application
unassigned |
3
0 |
| 3.4.23.49 | Bone Resorption |
9286755 |
Peptide aldehyde inhibitors of cathepsin K inhibit bone resorption both in vitro and in vivo. |
causal interaction
therapeutic application
unassigned |
3
4
0 |
| 3.4.23.49 | Borna Disease |
9557754 |
Processing of the Borna disease virus glycoprotein gp94 by the subtilisin-like endoprotease furin. |
unassigned |
0 |
| 3.4.23.49 | Botulism |
24583693 |
Direct biosensor detection of botulinum neurotoxin endopeptidase activity in sera from patients with type A botulism. |
causal interaction
diagnostic usage
ongoing research
unassigned |
1
3
2
0 |
| 3.4.23.49 | Breast Neoplasms |
30076522 |
Heterologous expression and characterization of the aspartic endoprotease Pep4um from Ustilago maydis, a homolog of the human Chatepsin D, an important breast cancer therapeutic target. |
causal interaction
ongoing research
unassigned |
3
3
0 |
| 3.4.23.49 | Breast Neoplasms |
31518603 |
Deubiquitination and stabilization of estrogen receptor ? by ubiquitin-specific protease 7 promotes breast tumorigenesis. |
ongoing research
therapeutic application
unassigned |
1
1
0 |
| 3.4.23.49 | Breast Neoplasms |
32922122 |
Ubiquitin-specific protease 7 downregulation suppresses breast cancer in vitro. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
2
1
2
2 |
| 3.4.23.49 | Carcinogenesis |
30179224 |
Ubiquitin-specific protease 7 sustains DNA damage response and promotes cervical carcinogenesis. |
causal interaction
unassigned |
2
0 |
