EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   3.4.21.B7 | Angioedemas, Hereditary |
26371246 |
The Levels of the Lectin Pathway Serine Protease MASP-1 and Its Complex Formation with C1 Inhibitor Are Linked to the Severity of Hereditary Angioedema. |
causal interaction
unassigned |
2
0 |
| 3.4.21.B7 | Arthritis |
20870940 |
Essential role of complement mannose-binding lectin-associated serine proteases-1/3 in the murine collagen antibody-induced model of inflammatory arthritis. |
causal interaction
ongoing research
unassigned |
1
4
0 |
| 3.4.21.B7 | Arthritis |
27707997 |
Mannan-Binding Lectin-Associated Serine Protease 1/3 Cleavage of Pro-Factor D into Factor D In Vivo and Attenuation of Collagen Antibody-Induced Arthritis through Their Targeted Inhibition by RNA Interference-Mediated Gene Silencing. |
causal interaction
unassigned |
2
0 |
| 3.4.21.B7 | Arthritis |
32153567 |
Key Components of the Complement Lectin Pathway Are Not Only Required for the Development of Inflammatory Arthritis but Also Regulate the Transcription of Factor D. |
causal interaction
ongoing research
unassigned |
1
4
0 |
| 3.4.21.B7 | Atherosclerosis |
27055907 |
Distinct Longitudinal Associations of MBL, MASP-1, MASP-2, MASP-3, and MAp44 With Endothelial Dysfunction and Intima-Media Thickness: The Cohort on Diabetes and Atherosclerosis Maastricht (CODAM) Study. |
ongoing research
unassigned |
3
0 |
| 3.4.21.B7 | Autoimmune Diseases |
18498410 |
Circulating levels of mannan-binding lectin (MBL) and MBL-associated serine protease 2 in endemic pemphigus foliaceus. |
causal interaction
unassigned |
4
0 |
| 3.4.21.B7 | Bacterial Infections |
21832079 |
Functional characterization of a ficolin-mediated complement pathway in amphioxus. |
unassigned |
0 |
| 3.4.21.B7 | Bacterial Infections |
28479400 |
Mannan-binding lectin-associated serine protease-1 (MASP-1) mediates immune responses against Aeromonas hydrophila in vitro and in vivo in grass carp. |
unassigned |
0 |
| 3.4.21.B7 | Bacterial Infections |
29475986 |
Cutting Edge: A New Player in the Alternative Complement Pathway, MASP-1 Is Essential for LPS-Induced, but Not for Zymosan-Induced, Alternative Pathway Activation. |
therapeutic application
unassigned |
3
0 |
| 3.4.21.B7 | Blindness |
27605007 |
Proteomics-based identification and validation of novel plasma biomarkers phospholipid transfer protein and mannan-binding lectin serine protease-1 in age-related macular degeneration. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
3
3
4
0 |
