EC Number   |
Disease |
PubMed ID |
Title of Publication  |
Category |
Confidence Level |
|---|
   2.4.1.94 | Neurodegenerative Diseases |
16051707 |
A Caenorhabditis elegans model of insulin resistance: altered macronutrient storage and dauer formation in an OGT-1 knockout. |
causal interaction
unassigned |
2
0 |
| 2.4.1.94 | Intellectual Disability |
31627256 |
A missense mutation in the catalytic domain of O-GlcNAc transferase links perturbations in protein O-GlcNAcylation to X-linked intellectual disability. |
causal interaction
unassigned |
2
0 |
| 2.4.1.94 | Colorectal Neoplasms |
26252736 |
Alteration of O-GlcNAcylation affects serine phosphorylation and regulates gene expression and activity of pyruvate kinase M2 in colorectal cancer cells. |
diagnostic usage
ongoing research
unassigned |
1
3
0 |
| 2.4.1.94 | Insulin Resistance |
12136128 |
Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia. |
causal interaction
therapeutic application
unassigned |
3
1
0 |
| 2.4.1.94 | Intellectual Disability |
32080367 |
An intellectual disability syndrome with single-nucleotide variants in O-GlcNAc transferase. |
unassigned |
0 |
| 2.4.1.94 | Melanoma, Experimental |
28536142 |
Augmented TME O-GlcNAcylation Promotes Tumor Proliferation through the Inhibition of p38 MAPK. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
3
1
0 |
| 2.4.1.94 | Neoplasms |
28536142 |
Augmented TME O-GlcNAcylation Promotes Tumor Proliferation through the Inhibition of p38 MAPK. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
3
1
0 |
| 2.4.1.94 | Neoplasms |
28670495 |
Bitterness in sugar: O-GlcNAcylation aggravates pre-B acute lymphocytic leukemia through glycolysis via the PI3K/Akt/c-Myc pathway. |
unassigned |
0 |
| 2.4.1.94 | Urinary Bladder Neoplasms |
32174982 |
Blockage of O-linked GlcNAcylation induces AMPK-dependent autophagy in bladder cancer cells. |
unassigned |
0 |
| 2.4.1.94 | Aortic Valve Stenosis |
22128088 |
Cardiac O-GlcNAc signaling is increased in hypertrophy and heart failure. |
ongoing research
unassigned |
2
0 |
