EC Number |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
---|
1.8.1.8 | Acidosis |
33449853 |
CaMKII? Met281/282 oxidation is not required for recovery of calcium transients during acidosis. |
causal interaction ongoing research therapeutic application unassigned |
1 2 1 0 |
1.8.1.8 | Acidosis, Lactic |
28064324 |
Mitochondrial iron-sulfur cluster biogenesis from molecular understanding to clinical disease. |
causal interaction unassigned |
4 0 |
1.8.1.8 | Alzheimer Disease |
24270206 |
Alteration of thioredoxin and glutaredoxin in the progression of Alzheimer's disease. |
causal interaction diagnostic usage unassigned |
4 2 0 |
1.8.1.8 | Anemia |
17485548 |
The human counterpart of zebrafish shiraz shows sideroblastic-like microcytic anemia and iron overload. |
unassigned |
0 |
1.8.1.8 | Anemia |
20364084 |
Glutaredoxin 5 deficiency causes sideroblastic anemia by specifically impairing heme biosynthesis and depleting cytosolic iron in human erythroblasts. |
causal interaction ongoing research unassigned |
3 1 0 |
1.8.1.8 | Anemia, Hypochromic |
16110529 |
Deficiency of glutaredoxin 5 reveals Fe-S clusters are required for vertebrate haem synthesis. |
unassigned |
0 |
1.8.1.8 | Anemia, Sideroblastic |
18606475 |
Iron-sulfur cluster biogenesis and human disease. |
causal interaction unassigned |
3 0 |
1.8.1.8 | Anemia, Sideroblastic |
20364084 |
Glutaredoxin 5 deficiency causes sideroblastic anemia by specifically impairing heme biosynthesis and depleting cytosolic iron in human erythroblasts. |
causal interaction ongoing research unassigned |
3 1 0 |
1.8.1.8 | Anemia, Sideroblastic |
20481466 |
Human iron-sulfur cluster assembly, cellular iron homeostasis, and disease. |
unassigned |
0 |
1.8.1.8 | Astrocytoma |
27180086 |
Methylmercury alters glutathione homeostasis by inhibiting glutaredoxin 1 and enhancing glutathione biosynthesis in cultured human astrocytoma cells. |
ongoing research unassigned |
4 0 |