EC Number |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
---|
1.5.1.33 | gtp cyclohydrolase i deficiency |
31202265 |
GTP-Cyclohydrolase I deficiency presenting as malignant hyperphenylalaninemia, recurrent hyperthermia and progressive neurological dysfunction in a South Asian child - a case report. |
causal interaction diagnostic usage therapeutic application unassigned |
4 3 1 0 |
1.5.1.33 | Leishmaniasis |
19916554 |
Structure-based design of pteridine reductase inhibitors targeting African sleeping sickness and the leishmaniases. |
therapeutic application unassigned |
3 0 |
1.5.1.33 | Leishmaniasis |
31370699 |
Targeting pteridine reductase 1 and dihydrofolate reductase: the old is a new trend for leishmaniasis drug discovery. |
therapeutic application unassigned |
4 0 |
1.5.1.33 | Leishmaniasis |
31702401 |
Structure based designing of benzimidazole/benzoxazole derivatives as anti-leishmanial agents. |
therapeutic application unassigned |
4 0 |
1.5.1.33 | Leishmaniasis, Visceral |
21115787 |
In silico screening, structure-activity relationship, and biologic evaluation of selective pteridine reductase inhibitors targeting visceral leishmaniasis. |
causal interaction therapeutic application unassigned |
2 4 0 |
1.5.1.33 | pteridine reductase deficiency |
691345 |
[Pteridine reductase deficiency] |
causal interaction unassigned |
4 0 |
1.5.1.33 | Trypanosomiasis, African |
16968221 |
Structure and reactivity of Trypanosoma brucei pteridine reductase: inhibition by the archetypal antifolate methotrexate. |
therapeutic application unassigned |
4 0 |
1.5.1.33 | Trypanosomiasis, African |
19527033 |
One scaffold, three binding modes: novel and selective pteridine reductase 1 inhibitors derived from fragment hits discovered by virtual screening. |
therapeutic application unassigned |
4 0 |
1.5.1.33 | Trypanosomiasis, African |
19916554 |
Structure-based design of pteridine reductase inhibitors targeting African sleeping sickness and the leishmaniases. |
therapeutic application unassigned |
3 0 |
1.5.1.33 | Trypanosomiasis, African |
27485569 |
Pharmacophore Mapping, In Silico Screening and Molecular Docking to Identify Selective Trypanosoma brucei Pteridine Reductase Inhibitors. |
therapeutic application unassigned |
2 0 |