EC Number |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
---|
1.14.14.19 | Breast Neoplasms |
161434 |
Metabolism of pregnenolone by human breast cancer. Evidence for 17 alpha-hydroxylase and 17,20-lyase. |
ongoing research therapeutic application unassigned |
1 1 0 |
1.14.14.19 | Neoplasms |
161434 |
Metabolism of pregnenolone by human breast cancer. Evidence for 17 alpha-hydroxylase and 17,20-lyase. |
ongoing research therapeutic application unassigned |
1 1 0 |
1.14.14.19 | Disorder of Sex Development, 46,XY |
1003059 |
Production of male pseudohermaphroditism in rats by two new inhibitors of steroid 17alpha-hydroxylase and C 17-20 lyase. |
therapeutic application unassigned |
3 0 |
1.14.14.19 | Herpes Zoster |
1319681 |
Studies of adrenal steroidogenic enzymes in guinea pigs. |
ongoing research unassigned |
2 0 |
1.14.14.19 | steroid 17alpha-monooxygenase deficiency |
1515452 |
Molecular basis of apparent isolated 17,20-lyase deficiency: compound heterozygous mutations in the C-terminal region (Arg(496)----Cys, Gln(461)----Stop) actually cause combined 17 alpha-hydroxylase/17,20-lyase deficiency. |
causal interaction therapeutic application unassigned |
4 1 0 |
1.14.14.19 | Prostatic Neoplasms |
1606043 |
4-pregnene-3-one-20 beta-carboxaldehyde: a potent inhibitor of 17 alpha-hydroxylase/C17,20-lyase and of 5 alpha-reductase. |
therapeutic application unassigned |
1 0 |
1.14.14.19 | Pituitary ACTH Hypersecretion |
1655322 |
Ketoconazole and plasma and urine steroid levels in Cushing's disease. |
therapeutic application unassigned |
1 0 |
1.14.14.19 | steroid 17alpha-monooxygenase deficiency |
2166072 |
A case of male pseudohermaphroditism due to 17 alpha-hydroxylase deficiency and hormonal profiles in the nuclear family. |
causal interaction diagnostic usage unassigned |
3 3 0 |
1.14.14.19 | steroid 17alpha-monooxygenase deficiency |
2843762 |
Structural characterization of normal and mutant human steroid 17 alpha-hydroxylase genes: molecular basis of one example of combined 17 alpha-hydroxylase/17,20 lyase deficiency. |
causal interaction unassigned |
3 0 |
1.14.14.19 | Pituitary ACTH Hypersecretion |
3023421 |
Use of ketoconazole in the treatment of Cushing's syndrome. |
causal interaction therapeutic application unassigned |
1 1 0 |