EC Number   |
Disease |
PubMed ID |
Title of Publication  |
Category |
Confidence Level |
|---|
   1.14.11.67 | Mental Retardation, X-Linked |
20181063 |
A distinctive gene expression fingerprint in mentally retarded male patients reflects disease-causing defects in the histone demethylase KDM5C. |
causal interaction
therapeutic application
unassigned |
1
1
0 |
| 1.14.11.67 | [histone h3]-trimethyl-l-lysine4 demethylase deficiency |
20181063 |
A distinctive gene expression fingerprint in mentally retarded male patients reflects disease-causing defects in the histone demethylase KDM5C. |
causal interaction
therapeutic application
unassigned |
1
1
0 |
| 1.14.11.67 | Breast Neoplasms |
29282222 |
A KDM5 Inhibitor Increases Global H3K4 Trimethylation Occupancy and Enhances the Biological Efficacy of 5-Aza-2'-Deoxycytidine. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
1
3
0 |
| 1.14.11.67 | Neoplasms |
29282222 |
A KDM5 Inhibitor Increases Global H3K4 Trimethylation Occupancy and Enhances the Biological Efficacy of 5-Aza-2'-Deoxycytidine. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
1
3
0 |
| 1.14.11.67 | Intellectual Disability |
26804915 |
A Mouse Model of X-linked Intellectual Disability Associated with Impaired Removal of Histone Methylation. |
ongoing research
therapeutic application
unassigned |
1
1
0 |
| 1.14.11.67 | Memory Disorders |
26804915 |
A Mouse Model of X-linked Intellectual Disability Associated with Impaired Removal of Histone Methylation. |
ongoing research
therapeutic application
unassigned |
1
1
0 |
| 1.14.11.67 | Intellectual Disability |
22326837 |
A novel c.2T > C mutation of the KDM5C/JARID1C gene in one large family with X-linked intellectual disability. |
causal interaction
unassigned |
2
0 |
| 1.14.11.67 | Ataxia |
34530748 |
A novel de novo KDM5C variant in a female with global developmental delay and ataxia: a case report. |
causal interaction
therapeutic application
unassigned |
4
1
0 |
| 1.14.11.67 | Intellectual Disability |
34530748 |
A novel de novo KDM5C variant in a female with global developmental delay and ataxia: a case report. |
causal interaction
therapeutic application
unassigned |
4
1
0 |
| 1.14.11.67 | Movement Disorders |
34530748 |
A novel de novo KDM5C variant in a female with global developmental delay and ataxia: a case report. |
causal interaction
therapeutic application
unassigned |
4
1
0 |
