EC Number   |
Disease |
PubMed ID |
Title of Publication  |
Category |
Confidence Level |
|---|
   2.4.2.29 | Dysentery, Bacillary |
11178905 |
A new target for shigellosis: rational design and crystallographic studies of inhibitors of tRNA-guanine transglycosylase. |
therapeutic application
unassigned |
4
0 |
| 2.4.2.29 | Colonic Neoplasms |
1378304 |
Absence of tRNA-guanine transglycosylase in a human colon adenocarcinoma cell line. |
ongoing research
unassigned |
4
0 |
| 2.4.2.29 | Dysentery, Bacillary |
26991861 |
An Immucillin-based Transition State-Analogous Inhibitor of tRNA-Guanine Transglycosylase (TGT). |
causal interaction
therapeutic application
unassigned |
1
4
0 |
| 2.4.2.29 | Neoplasms |
6844700 |
Characterization and analysis of oncofetal tRNA and its possible application for cancer diagnosis and therapy. |
causal interaction
unassigned |
2
0 |
| 2.4.2.29 | Dysentery, Bacillary |
19199329 |
Crystal structure analysis and in silico pKa calculations suggest strong pKa shifts of ligands as driving force for high-affinity binding to TGT. |
causal interaction
unassigned |
1
0 |
| 2.4.2.29 | Liver Neoplasms, Experimental |
360213 |
Detection of unique tRNA species in tumor tissues by Escherichia coli guanine insertion enzyme. |
ongoing research
therapeutic application
unassigned |
2
2
0 |
| 2.4.2.29 | Neoplasms |
360213 |
Detection of unique tRNA species in tumor tissues by Escherichia coli guanine insertion enzyme. |
ongoing research
therapeutic application
unassigned |
2
2
0 |
| 2.4.2.29 | Colonic Neoplasms |
15246567 |
Elevated expression level of 60-kDa subunit of tRNA-guanine transglycosylase in colon cancer. |
causal interaction
diagnostic usage
unassigned |
2
3
0 |
| 2.4.2.29 | Dysentery, Bacillary |
32515955 |
Fragment Screening Hit Draws Attention to a Novel Transient Pocket Adjacent to the Recognition Site of the tRNA-Modifying Enzyme TGT. |
unassigned |
0 |
| 2.4.2.29 | Dysentery, Bacillary |
19746363 |
High-Affinity Inhibitors of tRNA-Guanine Transglycosylase Replacing the Function of a Structural Water Cluster. |
therapeutic application
unassigned |
1
0 |
