Information on EC - tRNA-guanosine34 preQ1 transglycosylase

for references in articles please use BRENDA:EC2.4.2.29
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EC Tree
     2 Transferases
         2.4 Glycosyltransferases
             2.4.2 Pentosyltransferases
       tRNA-guanosine34 preQ1 transglycosylase
IUBMB Comments
Certain prokaryotic and eukaryotic tRNAs contain the modified base queuine at position 34. In eubacteria, which produce queuine de novo, the enzyme catalyses the exchange of guanine with the queuine precursor preQ1, which is ultimately modified to queuosine . The enzyme can also use an earlier intermediate, preQ0, to replace guanine in unmodified tRNATyr and tRNAAsn . This enzyme acts after EC, preQ1 synthase, in the queuine-biosynthesis pathway. cf. EC, tRNA-guanosine34 queuine transglycosylase.
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The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
ArcTGT, guanine insertion enzyme, guanine, queuine-tRNA transglycosylase, Q-insertase, QTRT1, QueTGT, queuine insertase, queuine tRNA ribosyltransferase, queuine tRNA-ribosyltransferase, queuine tRNA-ribosyltransferase subunit 1, more
guanine34 in tRNA + 7-aminomethyl-7-carbaguanine = 7-aminomethyl-7-carbaguanine34 in tRNA + guanine
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