EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category  |
Confidence Level |
|---|
   3.5.3.18 | Arthritis, Rheumatoid |
21920447 |
Elevated dimethylarginine dimethylaminohydrolase (DDAH) activity in rheumatoid arthritis and spondyloarthritis. |
causal interaction
diagnostic usage
unassigned |
4
2
0 |
| 3.5.3.18 | Atherosclerosis |
17293168 |
Taurine protects against low-density lipoprotein-induced endothelial dysfunction by the DDAH/ADMA pathway. |
causal interaction
therapeutic application
unassigned |
4
1
0 |
| 3.5.3.18 | Atherosclerosis |
20348244 |
Dimethylarginine dimethylaminohydrolase overexpression ameliorates atherosclerosis in apolipoprotein E-deficient mice by lowering asymmetric dimethylarginine. |
causal interaction
therapeutic application
unassigned |
3
4
0 |
| 3.5.3.18 | Atherosclerosis |
33535073 |
Treatment of atherosclerosis through transplantation of endothelial progenitor cells overexpressing dimethylarginine dimethylaminohydrolase (DDAH) in rabbits. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
2
4
0 |
| 3.5.3.18 | Cardiomegaly |
28819685 |
Cardiomyocyte dimethylarginine dimethylaminohydrolase-1 (DDAH1) plays an important role in attenuating ventricular hypertrophy and dysfunction. |
causal interaction
therapeutic application
unassigned |
1
2
0 |
| 3.5.3.18 | Cardiomegaly |
32762558 |
Enhanced dimethylarginine degradation improves coronary flow reserve and exercise tolerance in Duchenne muscular dystrophy carrier mice. |
causal interaction
ongoing research
therapeutic application
unassigned |
1
1
2
0 |
| 3.5.3.18 | Coronary Artery Disease |
16144995 |
Dimethylarginine dimethylaminohydrolase overexpression suppresses graft coronary artery disease. |
causal interaction
therapeutic application
unassigned |
4
1
0 |
| 3.5.3.18 | Coronary Artery Disease |
30284143 |
AGXT2 and DDAH-1 genetic variants are highly correlated with serum ADMA and SDMA levels and with incidence of coronary artery disease in Egyptians. |
causal interaction
diagnostic usage
unassigned |
3
2
0 |
| 3.5.3.18 | Coronary Artery Disease |
31409409 |
A functional variant of the dimethylarginine dimethylaminohydrolase-2 gene is associated with myocardial infarction in type 2 diabetic patients. |
causal interaction
diagnostic usage
unassigned |
4
4
0 |
| 3.5.3.18 | Demyelinating Diseases |
34270117 |
Dimethylarginine dimethylaminohydrolase 1 as a novel regulator of oligodendrocyte differentiation in the central nervous system remyelination. |
causal interaction
therapeutic application
unassigned |
2
4
0 |
