EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category  |
Confidence Level |
|---|
   3.5.3.18 | Diabetes Mellitus |
25701782 |
Accelerated onset of senescence of endothelial progenitor cells in patients with type 2 diabetes mellitus: Role of dimethylarginine dimethylaminohydrolase 2 and asymmetric dimethylarginine. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
4
3
0 |
| 3.5.3.18 | Diabetes Mellitus |
27359292 |
ASYMMETRIC DIMETHYLARGININE LEVELS AND ATHEROSCLEROSIS MARKERS IN CUSHING SYNDROME. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
4
4
2
0 |
| 3.5.3.18 | Heart Failure |
25310909 |
Cardioprotective effects of oxymatrine on isoproterenol-induced heart failure via regulation of DDAH/ADMA metabolism pathway in rats. |
causal interaction
unassigned |
3
0 |
| 3.5.3.18 | Hypertension |
12805079 |
Asymmetric dimethylarginine causes hypertension and cardiac dysfunction in humans and is actively metabolized by dimethylarginine dimethylaminohydrolase. |
causal interaction
unassigned |
2
0 |
| 3.5.3.18 | Hypertension |
19666123 |
Polymorphisms in the promoter region of the dimethylarginine dimethylaminohydrolase 2 gene are associated with prevalence of hypertension. |
causal interaction
therapeutic application
unassigned |
4
1
0 |
| 3.5.3.18 | Hypertension, Pulmonary |
12952847 |
Evidence for dysregulation of dimethylarginine dimethylaminohydrolase I in chronic hypoxia-induced pulmonary hypertension. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
3
1
0 |
| 3.5.3.18 | Hypertension, Pulmonary |
15827267 |
Increased levels and reduced catabolism of asymmetric and symmetric dimethylarginines in pulmonary hypertension. |
causal interaction
therapeutic application
unassigned |
1
1
0 |
| 3.5.3.18 | Hypertension, Pulmonary |
20840872 |
Involvement of asymmetric dimethylarginine and Rho kinase in the vascular remodeling in monocrotaline-induced pulmonary hypertension. |
causal interaction
unassigned |
3
0 |
| 3.5.3.18 | Hypertension, Pulmonary |
21641341 |
Rosuvastatin attenuates monocrotaline-induced pulmonary hypertension via regulation of Akt/eNOS signaling and asymmetric dimethylarginine metabolism. |
causal interaction
therapeutic application
unassigned |
3
1
0 |
| 3.5.3.18 | Hypertension, Pulmonary |
24895913 |
miR-21/DDAH1 pathway regulates pulmonary vascular responses to hypoxia. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
2
1
2 |
