EC Number   |
Disease |
PubMed ID  |
Title of Publication |
Category |
Confidence Level |
|---|
   3.4.17.23 | Prostatic Hyperplasia |
11745466 |
The TMPRSS2 gene encoding transmembrane serine protease is overexpressed in a majority of prostate cancer patients: detection of mutated TMPRSS2 form in a case of aggressive disease. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
4
4
2 |
| 3.4.17.23 | Prostatic Neoplasms |
11745466 |
The TMPRSS2 gene encoding transmembrane serine protease is overexpressed in a majority of prostate cancer patients: detection of mutated TMPRSS2 form in a case of aggressive disease. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
4
4
2 |
| 3.4.17.23 | Hypertension |
12075344 |
Angiotensin-converting enzyme 2 is an essential regulator of heart function. |
ongoing research
therapeutic application
unassigned |
3
1
0 |
| 3.4.17.23 | Diabetic Nephropathies |
12623933 |
Characterization of renal angiotensin-converting enzyme 2 in diabetic nephropathy. |
ongoing research
unassigned |
3
0 |
| 3.4.17.23 | Myocardial Infarction |
15007027 |
Upregulation of angiotensin-converting enzyme 2 after myocardial infarction by blockade of angiotensin II receptors. |
causal interaction
therapeutic application
unassigned |
2
3
0 |
| 3.4.17.23 | Diabetes Mellitus, Type 2 |
15078862 |
Increased ACE 2 and decreased ACE protein in renal tubules from diabetic mice: a renoprotective combination? |
ongoing research
unassigned |
4
0 |
| 3.4.17.23 | Hyperglycemia |
15078862 |
Increased ACE 2 and decreased ACE protein in renal tubules from diabetic mice: a renoprotective combination? |
ongoing research
unassigned |
4
0 |
| 3.4.17.23 | Obesity |
15078862 |
Increased ACE 2 and decreased ACE protein in renal tubules from diabetic mice: a renoprotective combination? |
ongoing research
unassigned |
4
0 |
| 3.4.17.23 | Infections |
15194496 |
Susceptibility to SARS coronavirus S protein-driven infection correlates with expression of angiotensin converting enzyme 2 and infection can be blocked by soluble receptor. |
causal interaction
diagnostic usage
unassigned |
4
1
0 |
| 3.4.17.23 | Severe Acute Respiratory Syndrome |
15194496 |
Susceptibility to SARS coronavirus S protein-driven infection correlates with expression of angiotensin converting enzyme 2 and infection can be blocked by soluble receptor. |
causal interaction
diagnostic usage
unassigned |
4
1
0 |
