EC Number   |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
|---|
   3.6.1.56 | 0.0000022 |
- |
TH1579 |
wild type enzyme, at pH 8.0 and 22°C |
756056 |
| 3.6.1.56 | 0.0000039 |
- |
TH1579 |
wild type enzyme, at pH 8.0 and 22°C |
756056 |
| 3.6.1.56 | 0.000004 |
- |
N4-cyclopropyl-6-(2,3-dichlorophenyl)pyrimidine-2,4-diamine |
wild type enzyme, at pH 8.0 and 22°C |
756056 |
| 3.6.1.56 | 0.0000068 |
- |
N4-cyclopropyl-6-(2,3-dichlorophenyl)pyrimidine-2,4-diamine |
wild type enzyme, at pH 8.0 and 22°C |
756056 |
| 3.6.1.56 | 0.0000225 |
- |
N4-cyclopropyl-6-(2,3-dichlorophenyl)pyrimidine-2,4-diamine |
mutant enzyme M116L, at pH 8.0 and 22°C |
756056 |
| 3.6.1.56 | 0.000032 |
- |
N4-cyclopropyl-6-(2,3-dichlorophenyl)pyrimidine-2,4-diamine |
mutant enzyme L116M, at pH 8.0 and 22°C |
756056 |
| 3.6.1.56 | 0.000132 |
- |
TH1579 |
wild type enzyme, at pH 8.0 and 22°C |
756056 |
| 3.6.1.56 | 0.000138 |
- |
N4-cyclopropyl-6-(2,3-dichlorophenyl)pyrimidine-2,4-diamine |
wild type enzyme, at pH 8.0 and 22°C |
756056 |
| 3.6.1.56 | 0.00021 |
- |
6-(1,3,3-trimethyl-6-azabicyclo[3.2.1]octan-6-yl)-9H-purine |
with 8-oxo-dGTP as substrate, at pH 7.5, temperature not specified in the publication |
756426 |
| 3.6.1.56 | 0.00023 |
- |
2-chloro-6-(1,3,3-trimethyl-6-azabicyclo[3.2.1]octan-6-yl)-9H-purine |
with 8-oxo-dGTP as substrate, at pH 7.5, temperature not specified in the publication |
756426 |
