EC Number |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
---|
1.14.15.4 | 0.0000002 |
- |
6-(5,8-dihydroisoquinolin-4-yl)-3,4-dihydroquinolin-2(1H)-one |
inhibition of CYP11B2, substrate 11-deoxycorticosterone, pH not specified in the publication, temperature not specified in the publication |
711434 |
1.14.15.4 | 0.0000002 |
- |
8-(isoquinolin-4-yl)-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one |
inhibition of CYP11B1, pH not specified in the publication, temperature not specified in the publication |
712715 |
1.14.15.4 | 0.0000002 |
- |
9-[6-(isoquinolin-4-yl)pyridin-3-yl]-2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolin-5-one |
inhibition of CYP11B1, pH not specified in the publication, temperature not specified in the publication |
712715 |
1.14.15.4 | 0.0000003 |
- |
(1S)-2-[2-[(1S)-1-(4-chlorophenyl)ethyl]-3,3-dioxido-1,2-dihydroimidazo[5,1-d][1,2,5]thiadiazin-4-yl]-1-phenylethanol |
inhibition of CYP11B2, pH not specified in the publication, temperature not specified in the publication |
711420 |
1.14.15.4 | 0.0000005 |
- |
4-((5-phenyl-1H-imidazol-1-yl)methyl)benzonitrile |
inhibition of CYP11B1, pH not specified in the publication, temperature not specified in the publication |
712695 |
1.14.15.4 | 0.0000006 |
- |
8-(5-methoxypyridin-3-yl)-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one |
inhibition of CYP11B1, pH not specified in the publication, temperature not specified in the publication |
712715 |
1.14.15.4 | 0.0000007 |
- |
2-[(1S)-1-(4-chlorophenyl)ethyl]-4-(3-methoxy-2-methylpropyl)-1,2-dihydroimidazo[5,1-d][1,2,5]thiadiazine 3,3-dioxide |
inhibition of CYP11B2, pH not specified in the publication, temperature not specified in the publication |
711420 |
1.14.15.4 | 0.0000007 |
- |
8-[5-(2-fluorophenyl)pyridin-3-yl]-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one |
inhibition of CYP11B1, pH not specified in the publication, temperature not specified in the publication |
712715 |
1.14.15.4 | 0.0000008 |
- |
2-[(1S)-1-(4-chlorophenyl)ethyl]-4-[(propan-2-yloxy)methyl]-1,2-dihydroimidazo[5,1-d][1,2,5]thiadiazine 3,3-dioxide |
inhibition of CYP11B2, pH not specified in the publication, temperature not specified in the publication |
711420 |
1.14.15.4 | 0.0000009 |
- |
8-[5-(4-fluorophenyl)pyridin-3-yl]-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one |
inhibition of CYP11B1, pH not specified in the publication, temperature not specified in the publication |
712715 |