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EC Number Crystallization (Commentary)
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.33hanging-drop vapour-diffusion method, crystallized in the presence of its product, CDP-glucose. Enzyme exists as a fully integrated hexamer with 32-point group symmetry
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.33hanging-drop vapour-diffusion method.The structure of the enzyme with bound MgCTP reveals that the binding pocket for the nucleotide is contained within one subunit rather than shared between two. Key side chains involved in nucleotide binding include Thr14, Arg15, Lys25, and Arg111
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