EC Number   |
|---|
    2.7.1.1 | crystal structure of hexokinase I from brain complexed with glucose and glucose 6-phosphate |
| 2.7.1.1 | crystal structure of the enzyme is determined at a resolution of 2.02 A, with Rcryst and Rfree values of 18.1% and 22.6%, respectively |
| 2.7.1.1 | crystal structures of hexokinase I dimers |
| 2.7.1.1 | crystallization employing ammonium sulfate, diammonium phosphate or polyethylene glycol 6000 at pH values of 8.0-9.5 gives seven different crystal forms of KlHxk1. Crystallographic data to 1.66 A resolution are obtained using synchrotron radiation |
| 2.7.1.1 | Crystals are grown in hanging drops, crystal structure of yeast hexokinase PI in complex with glucose and refined it at 2.95 A resolution |
| 2.7.1.1 | first structures of a glucokinase-glucose complex without activator, of glucokinase-glucose-AMP-PNP and of glucokinase-glucose-AMP-PNP with a bound activator are reported. All structures are extremely similar, thus demonstrating that binding of GK activators does not result in conformational changes of the active protein but in stabilization of the active form of glucokinase |
| 2.7.1.1 | hanging drop method |
| 2.7.1.1 | hanging drop vapor diffusion method at 25°C. Crystal structures of StHK in four different forms: (i) apo-form, (ii) binary complex with glucose, (iii) binary complex with ADP, and (iv) quaternary complex with xylose, Mg2+, and ADP. Forms i and iii are in the open state, and forms ii and iv are in the closed state, indicating that sugar binding induces a large conformational change, whereas ADP binding does not |
| 2.7.1.1 | hanging drop vapor diffusion method. Crystal structures of StHK in four different forms: (i) apo-form, (ii) binary complex with glucose, (iii) binary complex with ADP, and (iv) quaternary complex with xylose, Mg2+, and ADP. Forms i and iii are in the open state, and forms ii and iv are in the closed state, indicating that sugar binding induces a large conformational change, whereas ADP binding does not |
| 2.7.1.1 | hexokinase I from brain complexed with glucose and phosphate |
