EC Number |
Ki Value [mM] |
Ki Value maximum [mM] |
Inhibitor |
Reference |
---|
3.2.2.9 | 0.000000000047 |
- |
(3R,4S)-4-(4-chlorophenyl-thiomethyl)-1-[(9-deazaadenin-9-yl)methyl]-3-hydroxypyrrolidine |
25°C, pH 7.0, dissociation constant for the equilibrium complex of enzyme-inhibitor following slow-onset inhibition |
669334 |
3.2.2.9 | 0.0000000003 |
- |
(3R,4S)-4-(1-butylthiomethyl)-1-[(9-deaza-adenin-9-yl)methyl]-3-hydroxypyrrolidine |
pH and temperature not specified in the publication |
727674 |
3.2.2.9 | 0.00000000046 |
- |
(3R,4S)-4-(benzylthiomethyl)-1-[(9-deazaadenin-9-yl)methyl]-3-hydroxypyrrolidine |
25°C, pH 7.0, dissociation constant for the equilibrium complex of enzyme-inhibitor following slow-onset inhibition |
669334 |
3.2.2.9 | 0.000000002 |
- |
(1S)-5-(4-chlorophenylthio)-1-(9-deaza-adenin-9-yl)-1,4-dideoxy-1,4-imino-D-ribitol |
25°C, pH 7.0,dissociation constant for the equilibrium complex of enzyme-inhibitor following slow-onset inhibition |
669334 |
3.2.2.9 | 0.000000002 |
- |
(3R,4S)-1-[(9-deazaadenin-9-yl)methyl]-3-hydroxy-4-(methylthiomethyl)pyrrolidine |
25°C, pH 7.0, dissociation constant for the equilibrium complex of enzyme-inhibitor following slow-onset inhibition |
669334 |
3.2.2.9 | 0.000000002 |
- |
(3R,4S)-1-[(9-deazaadenin-9-yl)methyl]3-hydroxy-4-methylthiomethylpyrrolidine |
pH and temperature not specified in the publication |
727159 |
3.2.2.9 | 0.000000006 |
- |
(1S)-5-(4-chlorophenylthio)-1-(9-deaza-adenin-9-yl)-1,4-dideoxy-1,4-imino-D-ribitol |
25°C, pH 7.0, dissociation constant for the equilibrium between enzyme and inhibitor before slow-onset inhibition |
669334 |
3.2.2.9 | 0.000000008 |
- |
(1S)-1-(9-deazaadenin-9-yl)-1,4-dideoxy-1,4-imino-5-(4-methylphenylthio)-D-ribitol |
25°C, pH 7.0, dissociation constant for the equilibrium between enzyme and inhibitor before slow-onset inhibition |
669334 |
3.2.2.9 | 0.000000009 |
- |
(1S)-1-(9-deazaadenin-9-yl)-1,4-dideoxy-1,4-imino-5-(3-methylphenylthio)-D-ribitol |
25°C, pH 7.0,dissociation constant for the equilibrium complex of enzyme-inhibitor following slow-onset inhibition |
669334 |
3.2.2.9 | 0.000000015 |
- |
(1S)-1-(9-deazaadenin-9-yl)-1,4-dideoxy-1,4-imino-5-(3-methylphenylthio)-D-ribitol |
25°C, pH 7.0, dissociation constant for the equilibrium between enzyme and inhibitor before slow-onset inhibition |
669334 |