EC Number |
Ki Value [mM] |
Ki Value maximum [mM] |
Inhibitor |
Reference |
---|
2.7.10.1 | -999 |
- |
more |
- |
661031 |
2.7.10.1 | 0.000002 |
- |
N-(1H-indazol-3-yl)-7,7-dimethyl-2-(1H-pyrazol-4-yl)-5,7-dihydrofuro[3,4-d]pyrimidin-4-amine |
pH and temperature not specified in the publication |
737831 |
2.7.10.1 | 0.000002 |
- |
N-(6-fluoro-1H-indazol-3-yl)-7,7-dimethyl-2-(1H-pyrazol-4-yl)-5,7-dihydrofuro[3,4-d]pyrimidin-4-amine |
pH and temperature not specified in the publication |
737831 |
2.7.10.1 | 0.000002 |
- |
N-(7-chloro-1H-indazol-3-yl)-7,7-dimethyl-2-(1H-pyrazol-4-yl)-5,7-dihydrofuro[3,4-d]pyrimidin-4-amine |
pH and temperature not specified in the publication |
737831 |
2.7.10.1 | 0.0000027 |
- |
5-[(1R)-1-methyl-2-morpholin-4-yl-2-oxoethoxy]-N-[1-(1,3-thiazol-2-ylmethyl)-1H-indazol-5-yl]quinazolin-4-amine |
inhibition versus erbB2 kinase |
691267 |
2.7.10.1 | 0.000003 |
- |
N-(7-fluoro-1H-indazol-3-yl)-7,7-dimethyl-2-(1H-pyrazol-4-yl)-5,7-dihydrofuro[3,4-d]pyrimidin-4-amine |
pH and temperature not specified in the publication |
737831 |
2.7.10.1 | 0.0000033 |
- |
erlotinib |
deletion mutant enzyme DELTA746-750 |
672910 |
2.7.10.1 | 0.000004 |
- |
N-(7-chloro-6-fluoro-1H-indazol-3-yl)-7,7-dimethyl-2-(1H-pyrazol-4-yl)-5,7-dihydrofuro[3,4-d]pyrimidin-4-amine |
pH and temperature not specified in the publication |
737831 |
2.7.10.1 | 0.000005 |
- |
N-(5,7-difluoro-1H-indazol-3-yl)-7,7-dimethyl-2-(1H-pyrazol-4-yl)-5,7-dihydrofuro[3,4-d]pyrimidin-4-amine |
pH and temperature not specified in the publication |
737831 |
2.7.10.1 | 0.0000056 |
- |
N-(1H-indazol-3-yl)-7,7-dimethyl-2-(1,3-thiazol-4-yl)-5,7-dihydrofuro[3,4-d]pyrimidin-4-amine |
pH and temperature not specified in the publication |
737831 |