EC Number   |
Ki Value [mM] |
Ki Value maximum [mM] |
Inhibitor |
Reference  |
|---|
   3.4.21.27 | 0.52 |
- |
Aprotinin |
L-pyroglutamyl-L-prolyl-L-arginyl-p-nitroanilide substrate, free FXIa |
667583 |
| 3.4.21.27 | 0.96 |
- |
Aprotinin |
FIX substrate, free FXIa |
667583 |
| 3.4.21.27 | 1.43 |
- |
leupeptin |
L-pyroglutamyl-L-prolyl-L-arginyl-p-nitroanilide substrate, free FXIa |
667583 |
| 3.4.21.27 | 2.91 |
- |
leupeptin |
FIX substrate, free FXIa |
667583 |
| 3.4.21.27 | 10.42 |
- |
Aprotinin |
FIX substrate, FXIa-FIX complex |
667583 |
| 3.4.21.27 | 19.12 |
- |
leupeptin |
FIX substrate, FXIa-FIX complex |
667583 |
| 3.4.21.27 | 209 |
- |
leupeptin |
L-pyroglutamyl-L-prolyl-L-arginyl-p-nitroanilide substrate, FXIa-FIX complex |
667583 |
| 3.4.21.27 | -999 |
- |
more |
second-order inhibition rate constants, wild-type and mutant enzymes with different inhibitors, overview |
683157 |
| 3.4.21.27 | -999 |
- |
more |
competition for platelet binding by the wild-type enzyme and mutants, overview |
683160 |
| 3.4.21.27 | 0.06 |
- |
4-aminobenzamidine |
37°C, recombinant wild-type enzyme, versus substrate S-2366 |
683167 |
