EC Number   |
Ki Value [mM] |
Ki Value maximum [mM] |
Inhibitor |
Reference |
|---|
    2.3.1.47 | 0.0153 |
- |
(R)-8-amino-7-oxononanoic acid |
competitive constant, pyridoxal 5'-phosphate form of enzyme, coupled assay at 37°C with 100 mM N-(2-hydroxyethyl)piperazine-N'-(2-propanesulfonic acid) buffer (pH 8.6), 10 mM ATP, 50 mM NaHCO3, 10 mM MgCl2, dithiobiotin syntetase, 0.1 mM pyridoxal 5'-phosphate, varicous concentrations of S-adenosyl-L-methionine and 9 microM (S)-8-amino-7-oxononanoic acid, 0.2-20 microM inhibitor |
702483 |
| 2.3.1.47 | 0.0162 |
- |
(R)-8-amino-7-oxononanoic acid |
uncompetitive constant, pyridoxamine 5'-phosphate form of enzyme, coupled assay at 37°C with 100 mM N-(2-hydroxyethyl)piperazine-N'-(2-propanesulfonic acid) buffer (pH 8.6), 10 mM ATP, 50 mM NaHCO3, 10 mM MgCl2, dithiobiotin syntetase, 0.1 mM pyridoxal 5'-phosphate, 2.5 mM S-adenosyl-L-methionine and various concentrations of (S)-8-amino-7-oxononanoic acid, 0.2-19.2 microM inhibitor |
702483 |
| 2.3.1.47 | 0.068 |
- |
4-carboxybutyl(1-amino-1-carboxyethyl)phosphonate |
- |
487054 |
| 2.3.1.47 | 0.08 |
- |
2-amino-3-hydroxy-2-methylnonadioic acid |
- |
487054 |
| 2.3.1.47 | 0.115 |
- |
D-KAPA |
pH 7.7, 25°C, recombinant enzyme |
674626 |
| 2.3.1.47 | 0.59 |
- |
D-alanine |
- |
487054 |
| 2.3.1.47 | 0.99 |
- |
L-cysteine |
- |
487051 |
| 2.3.1.47 | 1.24 |
- |
D-alanine |
- |
487051 |
| 2.3.1.47 | 1.5 |
- |
L-serine |
- |
487051 |
| 2.3.1.47 | 3.33 |
- |
glycine |
- |
487051 |
