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Information on EC 2.3.1.47 - 8-amino-7-oxononanoate synthase

for references in articles please use BRENDA:EC2.3.1.47

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IUBMB Comments

A pyridoxal-phosphate protein. The enzyme catalyses the decarboxylative condensation of L-alanine and pimeloyl-[acyl-carrier protein], a key step in the pathway for biotin biosynthesis. Pimeloyl-CoA can be used with lower efficiency .

The enzyme appears in viruses and cellular organisms

Synonyms
dapa at, 8-amino-7-oxononanoate synthase, 7,8-diaminopelargonic acid aminotransferase, 8-amino-7-oxopelargonate synthase, kapas, kapa synthase, biof protein, 7-keto-8-aminopelargonic acid synthase, atbiof, 7-keto-8-aminopelargonic acid synthetase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
pimeloyl-[acyl-carrier protein] + L-alanine = 8-amino-7-oxononanoate + CO2 + holo-[acyl-carrier protein]
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
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