EC Number |
Cofactor |
Reference |
---|
6.3.1.21 | ATP |
- |
760555, 760556, 760559, 761243, 761366, 761368 |
6.3.1.21 | more |
key amino acid side chains involved in binding the nonhydrolyzable ATP analogue AMP-PNP to the enzyme include Arg114, Lys155, Glu195, Glu203, and Glu267. Strikingly, the amino group of GAR that is formylated during the reaction lies at 2.8 A from one of the gamma-phosphoryl oxygens of the AMP-PNP |
760559 |
6.3.1.21 | more |
no activity with CTP, GTP, TTP, ITP, and aminoimidazolecarboxamide ribonucleotide triphosphate (ZTP) |
760555 |