EC Number |
Cofactor |
Reference |
---|
1.1.1.195 | more |
NADPH is about 4000fold less effective than NADH |
724592 |
1.1.1.195 | more |
the enzyme has a highly conserved Rossmann fold NAD(P)H/NAD(P)+ binding domain |
733569 |
1.1.1.195 | more |
the enzyme is highly cofactor specific and is active only in presence of NADP(H), exhibiting insignificant activity with NAD(H) (up to 3 mM) |
740539 |
1.1.1.195 | more |
the motif GLGGLG participates in binding the diophosphate group of NADP+ |
738304 |
1.1.1.195 | NAD+ |
- |
347815, 724592 |
1.1.1.195 | NADH |
- |
696846, 724592 |
1.1.1.195 | NADP+ |
- |
288228, 347801, 347815, 347819, 668545, 670531, 670569, 670620, 670637, 670974, 700841, 733569, 738304, 739331, 739335, 739876, 740176, 740239, 740539, 741116, 741132, 741161, 741217, 741288 |
1.1.1.195 | NADP+ |
A-specific |
347811, 347812, 347813 |
1.1.1.195 | NADP+ |
cofactor binding site structure determination and analysis |
670458 |
1.1.1.195 | NADPH |
- |
288233, 347801, 347808, 347815, 347818, 347819, 656400, 657055, 668545, 670531, 670569, 670637, 713262, 733569, 738304, 739331, 739335, 739529, 739876, 740176, 740239, 740539, 741161, 741217, 741288, 760238, 760990, 761170, 761184, 761743, 761954, 762138, 762142, 762157 |