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EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 6.5.1.352.2 - geranyl triphosphate - 707449
Display the word mapDisplay the reaction diagram Show all sequences 6.5.1.3-999 - more the kinetic mechanism of single-turnover nick sealing by T4 Rnl2-AMP is explored by using a rapid mix-quench method and the effects of 3'-OH mispairs and base damage lesions on the rates of nick 5'-adenylylation and phosphodiester synthesis is determined. With respect to the sealing of perfectly paired nicks the rates of step 2 catalysis are rapid (9.5-17.9/sec) and similar in magnitude to the step 3 rates (7.9-32/sec). Rnl2 is kinetically sensitive to all 3'-OH base mispairs 728789
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