EC Number   |
Turnover Number Minimum [1/s] |
Turnover Number Maximum [1/s] |
Substrate |
Reference |
|---|
   3.4.21.27 | 86 |
- |
L-pyroGlu-L-Pro-L-Arg-4-nitroanilide |
mutant enzyme K192E, in 50 mM Tris-HCl, 150 mM NaCl, 5 mM CaCl2, 0.5% (w/v) bovine serum albumin, pH 7.3, at 37°C |
717844 |
| 3.4.21.27 | 95 |
- |
L-pyroGlu-L-Pro-L-Arg-4-nitroanilide |
mutant enzyme E98A, in 50 mM Tris-HCl, 150 mM NaCl, 5 mM CaCl2, 0.5% (w/v) bovine serum albumin, pH 7.3, at 37°C |
717844 |
| 3.4.21.27 | 95 |
- |
L-pyroGlu-L-Pro-L-Arg-4-nitroanilide |
mutant enzyme K192A, in 50 mM Tris-HCl, 150 mM NaCl, 5 mM CaCl2, 0.5% (w/v) bovine serum albumin, pH 7.3, at 37°C |
717844 |
| 3.4.21.27 | 98 |
- |
L-pyroglutamyl-L-prolyl-L-argininyl-p-nitroanilide |
fXIa-catalytic domain-K170A mutant |
691011 |
| 3.4.21.27 | 110.2 |
- |
D-Ile-Pro-Arg-4-nitroanilide |
recombinant wild-type enzyme, pH 7.5, 37°C |
683169 |
| 3.4.21.27 | 113 |
- |
S-2366 |
37°C, recombinant wild-type enzyme |
683167 |
| 3.4.21.27 | 115 |
- |
L-pyroglutamyl-L-prolyl-L-argininyl-p-nitroanilide |
fXIa-catalytic domain-K170A/R171A/R173A mutant |
691011 |
| 3.4.21.27 | 115 |
- |
L-pyroglutamyl-L-prolyl-L-argininyl-p-nitroanilide |
fXIa-catalytic domain-R171A mutant |
691011 |
| 3.4.21.27 | 116 |
- |
L-pyroglutamyl-L-prolyl-L-argininyl-p-nitroanilide |
fXIa-catalytic domain-K179A mutant |
691011 |
| 3.4.21.27 | 117 |
- |
L-pyroglutamyl-L-prolyl-L-argininyl-p-nitroanilide |
fXIa-catalytic domain-K175A mutant |
691011 |
