EC Number |
Temperature Stability Minimum [°C] |
Temperature Stability Maximum [°C] |
Reference |
---|
3.6.1.56 | 50 |
- |
Tm-value for mutant enzyme L150A |
715460 |
3.6.1.56 | 55 |
- |
10 min, both types of MTH1 protein (Met83-MTH1 and Val83-MTH1) retain full activity until the temperature reaches 55°C |
716297 |
3.6.1.56 | 55 |
- |
10 min, wild type hMTH1 retains 94% of the activity in the untreated extracts, mutant enzyme L150A retains 26% of the activity in the untreated extracts |
715460 |
3.6.1.56 | 60 |
- |
5 min, Met83-MTH1 loses 31-46% of its activity, Val83-MTH1 retains full activity |
716297 |
3.6.1.56 | 61 |
- |
Tm-value for mutant enzyme V156A |
715460 |
3.6.1.56 | 65 |
- |
Tm-value for wild-type enzyme. 10 min, wild type hMTH1 retains 49% of the activity in the untreated extracts, mutant enzyme L150A retains 14% of the activity in the untreated extracts |
715460 |