EC Number |
---|
7.6.2.1 | - |
7.6.2.1 | ATP10C |
7.6.2.1 | Creation and study of strains lacking Dnf1, Dnf2 or both Dnf1 and Dnf2. The double mutant is defective in the inward translocalisation of NBD-labeled phosphatidylethanolamine, phosphatidylserine and phosphatidylcholine across the plasmamembrane. The loss of both Dnf1 and Dnf2 leads to an increased cell surface exposure of endogenous aminophospholipids. The double mutant is sensitive to low concentrations of Co2+, Ni2+, Zn2+, and Mn2+ |
7.6.2.1 | DNA and amino acid sequence analysis |
7.6.2.1 | DNA and amino acid sequence analysis, PLSCR1, PLSCR2 and PLSCR4 are closely clustered on the small arm of chromosome 3q23 |
7.6.2.1 | DNA and amino acid sequence analysis, PLSCR1, PLSCR2 and PLSCR4 are closely clustered on the small arm of chromosome 3q23. The region comprising residues M86-E118 in PLSCR1 interacts with the promoter of inositol 1,4,5-triphosphate receptor type 1 |
7.6.2.1 | DNA and amino acid sequence analysis, PLSCR3 is localized to chromosome 17 |
7.6.2.1 | expressed in COS-7 cells |
7.6.2.1 | expressed in HEK-293T cells |
7.6.2.1 | expressed in HeLa cells |