EC Number |
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1.14.14.25 | expressed in Mus musculus |
1.14.14.25 | expression Escherichia coli, HEK293 cells transfected with CYP46A1 |
1.14.14.25 | expression in Escherichia coli |
1.14.14.25 | expression in Escherichia coli, wild-type and trucation mutatants. All four mutants lack the N-terminal transmembrane region (residues 327), and, in addition, DELTA46A1 has a 4 His-tag fused to the C-terminus, HDELTA46A1 has the N-terminal 4 His-tag, HDELTA46A1DELTA has a 4 His-tag at the N-terminus and does not contain a proline-rich region at the C-terminus (residues 494499), and DELTA46A1DELTA lacks the C-terminal proline-rich region |
1.14.14.25 | full ORF expression clone p46+ including the full cyp46A1 mouse open reading frame. Cyp46A1 overexpressed in 10 days in vitro hippocampal neurons |
1.14.14.25 | full-length and truncated (DELTA2-50) CYP46A1 expressed in Escherichia coli membranes |
1.14.14.25 | gene CYP46A1, CYP46A1 restoration protects from Exp-HTT-induced striatal dysfunctions in vitro. CYP46A1 restoration in the striatum improves the motor phenotype of R6/2 mice |
1.14.14.25 | gene CYP46A1, expression analysis |
1.14.14.25 | gene CYP46A1, expressionin CHO-K1 cells and HEK-293 cells |
1.14.14.25 | gene CYP46A1, quantitative expression analysis |